巴基斯坦南部孕妇的风疹血清流行率及人口统计学特征分析

Rubella seroprevalence and demographic feature analysis in pregnant women from Southern Pakistan.

作者信息

Khan Aamir, Rahman Hazir, Noushin Rabia, Anjum Syed Ishtiaq, Saad Faryal, Ullah Kalim

机构信息

Department of Zoology, Kohat University of Science and Technology, Khyber Pakhtunkhwa.

Department of Microbiology, Kohat University of Science and Technology, Khyber Pakhtunkhwa.

出版信息

J Pak Med Assoc. 2019 Aug;69(8):959-963.

PMID:31431775

Abstract

The present study was conducted to estimate the prevalence of rubella infection in pregnant women of district Lakki Marwat leading to foetal death, abortion, premature birth or congenital rubella syndrome. A total of 200 blood samples were collected from pregnant women visiting different maternal health care centers of the study area. Sera samples were tested for rubella-specific IgG and IgM antibodies through ELISA. The overall sero-positivity rate for IgG was 16% and for IgM was 2.5% in the pregnant women respectively. A higher sero-positivity rate was observed in the age group of 26-33 years. Women of rural areas showed higher sero-positivity rate than urban areas. The high sero-prevalence of rubella in the pregnant women of the study area poses a serious threat to the developing foetus.

摘要

本研究旨在评估拉克基马尔瓦特地区导致胎儿死亡、流产、早产或先天性风疹综合征的孕妇风疹感染患病率。从前往研究区域不同孕产妇保健中心就诊的孕妇中总共采集了200份血样。通过酶联免疫吸附测定法检测血清样本中的风疹特异性IgG和IgM抗体。孕妇中IgG的总体血清阳性率分别为16%，IgM为2.5%。在26 - 33岁年龄组中观察到较高的血清阳性率。农村地区妇女的血清阳性率高于城市地区。研究区域孕妇中风疹的高血清流行率对发育中的胎儿构成严重威胁。