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Anti-EJ, anti-MDA5 double-positive chronic clinically amyopathic dermatomyositis: a case report.

作者信息

Takeuchi Yusuke, Hashimoto Motomu, Nakashima Ran, Tanaka Masao, Kuramoto Nobuo, Murakami Kosaku, Yoshifuji Hajime, Ohmura Koichiro, Mimori Tsuneyo

机构信息

Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Department of Advanced Medicine for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

出版信息

Rheumatol Adv Pract. 2018 Jun 23;2(2):rky022. doi: 10.1093/rap/rky022. eCollection 2018.

DOI:10.1093/rap/rky022
PMID:31431968
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6649910/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7db7/6649910/2a6e408be243/rky022f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7db7/6649910/2a6e408be243/rky022f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7db7/6649910/2a6e408be243/rky022f1.jpg

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2
Anti-MDA5 Positive Dermatomyositis Associated with Rapidly Progressive Interstitial Lung Disease and Correlation between Serum Ferritin Level and Treatment Response.抗MDA5阳性皮肌炎合并快速进展性间质性肺疾病及血清铁蛋白水平与治疗反应的相关性
Mediterr J Rheumatol. 2020 Mar 31;31(1):75-77. doi: 10.31138/mjr.31.1.75. eCollection 2020 Mar.
3
Differential clinical features of patients with clinically amyopathic dermatomyositis who have circulating anti-MDA5 autoantibodies with or without myositis-associated autoantibodies.伴或不伴肌炎相关自身抗体的临床无肌病性皮肌炎患者循环抗 MDA5 自身抗体的临床特征差异。
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A case of anti-MDA5-positive rapidly progressive interstitial lung disease in a patient with clinically amyopathic dermatomyositis ameliorated by rituximab, in addition to standard immunosuppressive treatment.一例临床无肌病性皮肌炎伴抗 MDA5 阳性快速进展性间质性肺病患者,在标准免疫抑制治疗的基础上联合利妥昔单抗治疗后病情改善。
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引用本文的文献

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The clinical features and prognoses of anti-MDA5 and anti-aminoacyl-tRNA synthetase antibody double-positive dermatomyositis patients.

本文引用的文献

1
Comparison of long-term prognosis and relapse of dermatomyositis complicated with interstitial pneumonia according to autoantibodies: anti-aminoacyl tRNA synthetase antibodies versus anti-melanoma differentiation-associated gene 5 antibody.根据自身抗体比较皮肌炎合并间质性肺炎的长期预后和复发情况:抗氨酰tRNA合成酶抗体与抗黑色素瘤分化相关基因5抗体的比较
Rheumatol Int. 2017 Aug;37(8):1335-1340. doi: 10.1007/s00296-017-3729-y. Epub 2017 Apr 27.
2
Antisynthetase syndrome: Pulmonary computed tomography findings of adult patients with antibodies to aminoacyl-tRNA synthetases.抗合成酶综合征:抗氨酰tRNA合成酶抗体成年患者的肺部计算机断层扫描结果
Eur J Radiol. 2016 Aug;85(8):1421-6. doi: 10.1016/j.ejrad.2016.05.012. Epub 2016 May 24.
3
抗 MDA5 和抗氨酰-tRNA 合成酶抗体双阳性皮肌炎患者的临床特征和预后。
Front Immunol. 2022 Aug 30;13:987841. doi: 10.3389/fimmu.2022.987841. eCollection 2022.
4
Dermatomyositis Which Was Double Positive for Anti-MDA5 and Anti-ARS Antibodies That Was Successfully Treated by Intensive Immunosuppressive Therapy.抗 MDA5 抗体和抗ARS 抗体双阳性皮肌炎经强化免疫抑制治疗后成功缓解
Intern Med. 2022;61(7):1085-1091. doi: 10.2169/internalmedicine.8579-21. Epub 2022 Apr 1.
5
Clinically amyopathic dermatomyositis with interstitial lung disease double-positive for anti-MDA5 and anti-PL12 antibodies.临床无肌病性皮肌炎合并间质性肺病,抗MDA5和抗PL12抗体双阳性。
Respir Med Case Rep. 2022 Feb 18;36:101606. doi: 10.1016/j.rmcr.2022.101606. eCollection 2022.
6
Double anti-PL-7 and anti-MDA-5 positive Amyopathic Dermatomyositis with rapidly progressive interstitial lung disease in a Hispanic patient.一名西班牙裔患者患有双抗PL - 7和抗MDA - 5阳性的无肌病性皮肌炎并伴有快速进展性间质性肺病。
BMC Pulm Med. 2020 Aug 15;20(1):220. doi: 10.1186/s12890-020-01256-x.
Clinical significance and new detection system of autoantibodies in myositis with interstitial lung disease.伴间质性肺疾病的肌炎中自身抗体的临床意义及新检测系统
Lupus. 2016 Jul;25(8):925-33. doi: 10.1177/0961203316651748.
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MDA5-positive dermatomyositis: an uncommon entity in Europe with variable clinical presentations.黑色素瘤分化相关基因5(MDA5)阳性皮肌炎:在欧洲是一种临床表现多样的罕见疾病。
Clin Mol Allergy. 2015 Nov 9;13:22. doi: 10.1186/s12948-015-0031-y. eCollection 2015.
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Common and distinct clinical features in adult patients with anti-aminoacyl-tRNA synthetase antibodies: heterogeneity within the syndrome.抗氨酰基-tRNA 合成酶抗体的成年患者的常见和独特临床特征:综合征内的异质性。
PLoS One. 2013;8(4):e60442. doi: 10.1371/journal.pone.0060442. Epub 2013 Apr 3.
6
HRCT features of interstitial lung disease in dermatomyositis with anti-CADM-140 antibody.皮肌炎合并抗 CADM-140 抗体患者的间质性肺疾病的 HRCT 特征。
Respir Med. 2011 Sep;105(9):1380-7. doi: 10.1016/j.rmed.2011.05.006. Epub 2011 May 31.