[特定抗脑膜炎球菌抗体在集体中脑膜炎球菌带菌状态传播中的作用评估]

[Evaluation of the role of specific antimeningococcal antibodies in the spread of meningococcal carrier states in collectives].

作者信息

Demina A A, Pokrovskiĭ V I, Kuz'menko S V, Deviatkina N P, Semina N A

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1979 Sep(9):18-23.

Abstract

The results of serological, bacteriological and epidemiological studies carried out in populations with different epidemic pattern of meningococcal infection are presented. A-group specific antibody was found to have the leading role in the intensity of the spread of meningococcal infection in the populations. The presence of antibody to this antigen in 16.7% of serum samples inhibited dissemination of meningococci in the populations. Simultaneously with an increase in the herd immunity level to 34.8% the attenuation of the active meningococcal dissemination cycle was observed. Meningococci isolated in the populations with different epidemic patterns of meningococcal infection were shown to have different ecological properties.

摘要

本文展示了在具有不同脑膜炎球菌感染流行模式的人群中进行的血清学、细菌学和流行病学研究结果。发现A群特异性抗体在人群中脑膜炎球菌感染传播强度方面起主导作用。16.7%的血清样本中存在针对该抗原的抗体，可抑制脑膜炎球菌在人群中的传播。随着群体免疫水平提高到34.8%，同时观察到活跃的脑膜炎球菌传播周期减弱。在具有不同脑膜炎球菌感染流行模式的人群中分离出的脑膜炎球菌显示出不同的生态学特性。