磁共振成像上具有高信号的生理性颅内钙化：病例报告及实验模型
Physiologic intracranial calcification with hyperintensity on MR imaging: case report and experimental model.
作者信息
Dell L A, Brown M S, Orrison W W, Eckel C G, Matwiyoff N A
机构信息
Center for Non-Invasive Diagnosis, University New Mexico, School of Medicine, Albuquerque 87131.
出版信息
AJNR Am J Neuroradiol. 1988 Nov-Dec;9(6):1145-8.
CT and MR imaging showed basal ganglia calcification that appeared as high signal intensity on T1-weighted images of a patient with pseudohypoparathyroidism. MR imaging of an experimental model of calcium phosphate suspensions showed a signal similar to that seen in the patient. Additionally, T1 and T2 relaxation times of the solutions were measured and showed decreases in both parameters with increasing calcium phosphate concentrations. Intracranial calcification can appear as high signal intensity on T1-weighted images. An experimental model shows that the calcium salt decreases the T1 of surrounding water. Therefore, calcium, and possibly other elements, may induce paramagnetic susceptibility effects.
CT和磁共振成像显示，假甲状旁腺功能减退患者的基底节钙化在T1加权图像上表现为高信号强度。磷酸钙悬浮液实验模型的磁共振成像显示出与该患者所见相似的信号。此外，还测量了溶液的T1和T2弛豫时间，结果显示随着磷酸钙浓度的增加，这两个参数均降低。颅内钙化在T1加权图像上可表现为高信号强度。一个实验模型表明，钙盐会降低周围水的T1。因此，钙以及可能的其他元素可能会诱发顺磁敏感性效应。
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