Bravo-Linares David, Acevedo-Melo Andrés M, Ruiz-Patiño Alejandro, Ricaurte Luisa, Lucio-Arias Diana, Cardona Andrés F
Rosario University, Bogotá, Colombia.
Foundation for Clinical and Applied Cancer Research, Bogotá, Colombia.
J Glob Oncol. 2019 Aug;5:1-10. doi: 10.1200/JGO.19.00164.
Cancer morbidity represents an increasing public health issue; this worldwide phenomenon also is true for emerging upper-middle-income countries, such as Colombia. The main purpose of this study was to uncover the relationship between scientific productivity and cancer-related mortality in our setting.
We conducted a temporal-trend ecologic study by means of bibliometric analysis from records of publications from SCOPUS database with Colombian institutional affiliations between 2000 and 2015. Productivity and overall mortality were estimated and compared using econometric modeling to identify potential correlations. Additional exploratory analyses per six most frequent cancer sites were performed.
Of 2,645 publication records retrieved, 1,464 (55.3%) met selection criteria to be classified as Colombian scientific production (interobserver agreement, 92.96%; κ = 0.859; 95% CI, 0.800 to 0.918). Overall, 79.6% of the records corresponded to original or in-press articles; furthermore, almost half (49.7%) embodied descriptive study designs. Selected records reported a median of five authors and three different affiliations per publication; 66% had been cited at least once up to September 2017. The most-studied cancer-specific locations were cervix (16.1%), breast (11.5%), and stomach (9.8%), but nonspecific locations had the largest combined participation (23.4%). An increasing trend in scientific productivity was correlated to decreasing trend in overall cancer mortality, which was reported as an inverse proportional relationship in the linear regression modeling ( = -0.958; < .001). Graphic analyses per cancer-specific sites revealed heterogeneous behaviors of this relationship.
Colombian cancer-specific scientific productivity demonstrated a steady growth as opposed to a decreasing mortality trend in the recent years. The research output is predominantly descriptive with relatively low interinstitutional partnership and low impact in the international scientific community.
癌症发病率是一个日益严重的公共卫生问题；这种全球现象在新兴的中高收入国家（如哥伦比亚）同样存在。本研究的主要目的是揭示我们环境中科学产出与癌症相关死亡率之间的关系。
我们通过文献计量分析进行了一项时间趋势生态学研究，数据来自2000年至2015年间SCOPUS数据库中具有哥伦比亚机构附属关系的出版物记录。使用计量经济学模型估计并比较生产力和总体死亡率，以确定潜在的相关性。对六个最常见的癌症部位进行了额外的探索性分析。
在检索到的2645条出版物记录中，1464条（55.3%）符合入选标准，被归类为哥伦比亚的科研成果（观察者间一致性为92.96%；κ = 0.859；95% CI，0.800至0.918）。总体而言，79.6%的记录对应于原创或即将发表的文章；此外，几乎一半（49.7%）采用描述性研究设计。入选记录显示，每份出版物的作者中位数为五人，不同附属机构中位数为三个；截至2017年9月，66%的记录至少被引用过一次。研究最多的癌症特定部位是子宫颈（16.1%）、乳腺（11.5%）和胃（9.8%），但非特定部位的综合参与度最高（23.4%）。科学产出的增长趋势与总体癌症死亡率的下降趋势相关，在线性回归模型中报告为反比例关系（ = -0.958； <.001）。针对特定癌症部位的图形分析显示了这种关系的异质性。
与近年来死亡率下降趋势相反，哥伦比亚特定癌症的科学产出呈现稳步增长。研究成果主要是描述性的，机构间合作相对较少，在国际科学界的影响力较低。
