Department of Microbiology, The Ohio State University, Columbus, Ohio, USA
Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, USA.
mSphere. 2019 Aug 21;4(4):e00578-19. doi: 10.1128/mSphere.00578-19.
Matt Anderson works in the field of genetics and infectious disease, with a focus on the human fungal pathogen In this mSphere of Influence article, he reflects on how two papers, "Gene Flow Contributes to Diversification of the Major Fungal Pathogen " (J. Ropars, C. Maufrais, D. Diogo, M. Marcet-Houben, A. Perin, et al., Nat Commun 9:2253, 2018, https://doi.org/10.1038/s41467-018-04787-4) and "Selection of Trisomy during Oropharyngeal Infection Results in a Commensal-Like Phenotype" (A. Forche, N. V. Solis, M. Swidergall, R. Thomas, A. Guyer, et al., PLoS Genet 15:e1008137, 2019, https://doi.org/10.1371/journal.pgen.1008137), made an impact on him by incorporating less commonly investigated mechanisms of genome evolution into the context of microbial adaptation.
马特·安德森(Matt Anderson)从事遗传学和传染病领域的工作,专注于人类真菌病原体。在这篇 mSphere 影响文章中,他反思了两篇论文,“基因流有助于主要真菌病原体的多样化”(J. Ropars,C. Maufrais,D. Diogo,M. Marcet-Houben,A. Perin,等,Nat Commun 9:2253,2018,https://doi.org/10.1038/s41467-018-04787-4)和“口咽感染过程中选择三体导致类似共生的表型”(A. Forche,N. V. Solis,M. Swidergall,R. Thomas,A. Guyer,等,PLoS Genet 15:e1008137,2019,https://doi.org/10.1371/journal.pgen.1008137),如何将较少研究的基因组进化机制纳入微生物适应的背景中,对他产生了影响。