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美国创伤性臂丛神经损伤的间接成本。

Indirect Cost of Traumatic Brachial Plexus Injuries in the United States.

机构信息

Division of Hand and Upper Extremity Surgery, Department of Orthopaedic Surgery (T.S.H., A.T., R.S., D.M.B., and C.J.D.), Department of Neurosurgery (W.Z.R.), and Division of Public Health Sciences, Department of Surgery (C.J.D.), Washington University School of Medicine, Saint Louis, Missouri.

出版信息

J Bone Joint Surg Am. 2019 Aug 21;101(16):e80. doi: 10.2106/JBJS.18.00658.

Abstract

BACKGROUND

Traumatic brachial plexus injuries (BPIs) disproportionately affect young, able-bodied individuals. Beyond direct costs associated with medical treatment, there are far-reaching indirect costs related to disability and lost productivity. Our objective was to estimate per-patient indirect cost associated with BPI.

METHODS

We estimated indirect costs as the sum of (1) short-term wage loss, (2) long-term wage loss, and (3) disability payments. Short-term (6-month) wage loss was the product of missed work days and the average earnings per day. The probability of return to work was derived from a systematic review of the literature, and long-term wage loss and disability payments were estimated. Monte Carlo simulation was used to perform a sensitivity analysis of long-term wage loss by varying age, sex, and return to work simultaneously. Disability benefits were estimated from U.S. Social Security Administration data. All cost estimates are in 2018 U.S. dollars.

RESULTS

A systematic review of the literature demonstrated that the patients with BPI had a mean age of 26.4 years, 90.5% were male, and manual labor was the most represented occupation. On the basis on these demographics, our base case was a 26-year-old American man working as a manual laborer prior to BPI, with an annual wage of $36,590. Monte Carlo simulation estimated a short-term wage loss of $22,740, a long-term wage loss of $737,551, and disability benefits of $353,671. The mean total indirect cost of traumatic BPI in the Monte Carlo simulations was $1,113,962 per patient over the post-injury lifetime (median: $801,723, interquartile range: $22,740 to $2,350,979). If the probability of the patient returning to work at a different, lower-paying job was doubled, the per-patient total indirect cost was $867,987.

CONCLUSIONS

BPI can have a far-reaching economic impact on both individuals and society. If surgical reconstruction enables patients with a BPI to return to work, the indirect cost of this injury decreases.

LEVEL OF EVIDENCE

Economic Level IV. See Instructions for Authors for a complete description of levels of evidence.

摘要

背景

创伤性臂丛神经损伤(BPIs)不成比例地影响年轻、健全的个体。除了与医疗相关的直接费用外,还有与残疾和生产力丧失相关的深远的间接费用。我们的目的是估计每位患者与 BPI 相关的间接成本。

方法

我们将间接成本估计为以下三项的总和:(1)短期工资损失,(2)长期工资损失,和(3)残疾津贴。短期(6 个月)工资损失是缺勤天数与每天平均收入的乘积。工作回归的概率来自对文献的系统回顾,长期工资损失和残疾津贴是根据此概率估计的。通过同时改变年龄、性别和工作回归概率,对长期工资损失进行蒙特卡罗模拟敏感性分析。残疾津贴是根据美国社会保障管理局的数据估算的。所有成本估算均以 2018 年美元为单位。

结果

文献系统回顾表明,BPIs 患者的平均年龄为 26.4 岁,90.5%为男性,体力劳动是最常见的职业。基于这些人口统计学特征,我们的基础病例是一名 26 岁的美国男性,在发生 BPI 之前从事体力劳动,年薪为 36590 美元。蒙特卡罗模拟估计短期工资损失为 22740 美元,长期工资损失为 737551 美元,残疾津贴为 353671 美元。在蒙特卡罗模拟中,创伤性 BPI 的平均总间接成本为每位患者在受伤后的一生中为 1113962 美元(中位数:801723 美元,四分位距:22740 美元至 2350979 美元)。如果患者返回工作的可能性翻倍,且工作为薪资金额较低的不同工作,每位患者的总间接成本为 867987 美元。

结论

BPI 可能对个人和社会产生深远的经济影响。如果手术重建使 BPI 患者能够重返工作岗位,那么这种伤害的间接成本将会降低。

证据水平

经济水平 IV。请参阅作者说明以获取完整的证据水平描述。

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