Gutierrez A E, Merino O R
Radiation Oncology Section, St. Joseph Hospital, Houston, TX 77002.
Int J Radiat Oncol Biol Phys. 1988 Dec;15(6):1317-22. doi: 10.1016/0360-3016(88)90226-x.
A total of 119 patients with a diagnosis of adenocarcinoma of the prostate (Stage B and C) were treated at St. Joseph Hospital Houston, Texas from 1971 through 1984 using a combination of radioactive gold seed implant and external irradiation. The prognostic significance of tumor grading and pelvic node involvement was analyzed. Five and 10-year survival for Stage B was 100% and 85% respectively; for Stage C it was 68% and 43% respectively. The cumulative 94% local control rate for Stage B and C cases obtained in this report suggests more effectiveness to control the disease locally with acceptable rate of complications, when radioactive gold seed implant is added.
1971年至1984年期间，德克萨斯州休斯顿圣约瑟夫医院对总共119例诊断为前列腺腺癌（B期和C期）的患者采用放射性金种子植入和外照射相结合的方法进行治疗。分析了肿瘤分级和盆腔淋巴结受累的预后意义。B期患者的5年和10年生存率分别为100%和85%；C期患者分别为68%和43%。本报告中B期和C期病例获得的累计94%的局部控制率表明，增加放射性金种子植入后，在并发症发生率可接受的情况下，对局部疾病的控制更有效。
