哈巴宁、麻风菌素和结核菌素在同源和异源分枝杆菌致敏豚鼠中的相对交叉反应性。
Relative cross reactivity of habanin, lepromin and tuberculin in guinea pigs sensitized with homologous and heterologous mycobacteria.
作者信息
Singh N B, Srivastava A, Gupta H P, Kumar A, Chaturvedi V K
机构信息
Division of Microbiology, Central Drug Research Institute, Lucknow, India.
出版信息
Indian J Lepr. 1988 Jul;60(3):407-12.
An atypical strain Mycobacterium habana has been studied for its antigenic cross reactivity with delayed type of hypersensitivity responses in guinea pigs. Guinea pigs sensitized with M. habana, M. leprae and M. tuberculosis when challenged with habanin, lepromin and tuberculin in criss-cross fashion have demonstrated strong cross reactivity with each other. Possibilities of developing M. habana as a vaccine against tuberculosis and/or leprosy has been discussed.
对一种非典型菌株哈瓦那分枝杆菌进行了研究，以探讨其与豚鼠迟发型超敏反应的抗原交叉反应性。用哈瓦那分枝杆菌、麻风分枝杆菌和结核分枝杆菌致敏的豚鼠，以交叉方式用哈瓦那菌素、麻风菌素和结核菌素进行攻击时，彼此之间表现出强烈的交叉反应性。还讨论了将哈瓦那分枝杆菌开发成抗结核病和/或麻风病疫苗的可能性。
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