尿嘧啶-碘𬭩（III）盐的合成及其作为核苷碱基合成模块的实际应用。

Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku-ku, Nagoya 468-8503, Japan.

College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Nojihigashi, Kusatsu, Shiga 525-8577, Japan.

Molecules. 2019 Aug 21;24(17):3034. doi: 10.3390/molecules24173034.

Iodonium(III) salts bearing uracil moieties have recently appeared in the literature, but their structural scope and utilization are limited because of their hygroscopic characteristics. In this study, we describe our detailed investigations for synthesizing a series of uracil iodonium(III) salts derived with various structural motifs and counterions. These new compounds have been utilized as attractive synthetic modules in constructing functionalized nucleobase and nucleosides

近年来，带有尿嘧啶部分的碘𬭩(III)盐在文献中出现，但由于其吸湿性特点，其结构范围和用途受到限制。在这项研究中，我们详细研究了合成一系列具有各种结构母核和抗衡离子的尿嘧啶碘𬭩(III)盐。这些新化合物已被用作构建功能化碱基和核苷的有吸引力的合成模块。