Sangsin Apiruk, Murakami Hideki, Shimizu Takaki, Kato Satoshi, Demura Satoru, Tsuchiya Hiroyuki
Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Spine Surg Relat Res. 2018 Jul 27;2(3):236-242. doi: 10.22603/ssrr.2018-0014. eCollection 2018.
L5 spondylectomy for the treatment of spinal tumor is a technically demanding surgery because of the complex anatomy of major vessels, the obscurity of the posterior exposure from the iliac wings, and the increased comparative size of the L5 vertebral body. In this study, we present a surgical technique of L5 spondylectomy, vertebral body removal, and anterior reconstruction for a case with solitary spinal metastatic renal cell carcinoma (RCC).
A 54-year-old man underwent right total nephrectomy for RCC one year ago. At the one-year postoperative follow-up, CT scan and MRI revealed a solitary L5 spinal metastasis. A two-stage posteroanterior approach was performed. To facilitate vertebral body removal, transverse processes were separated from the vertebral body by using the posterior approach. On the basis of the anterior approach, the vertebral body was removed via the interval space between the left common iliac vessels. Reconstruction was performed by using a liquid-nitrogen-frozen, tumor-bearing bone mixed with an autogenous bone graft in an expandable titanium cage.
No intraoperative complications were observed. Postoperatively, the patient exhibited muscle weakness in the tibialis anterior and extensor hallucis longus bilaterally but improved with time. Seven months after the operation, the patient was able to walk independently. At the recent 2.5-year follow-up, the local recurrence of lesions was nonexistent. The bone graft had fused with the adjacent vertebrae.
This report described a novel technique for L5 spondylectomy that can facilitate safe L5 vertebral body removal and demonstrated the effectiveness of liquid-nitrogen-frozen, tumor-bearing bone mixed with autogenous bone graft in anterior reconstruction both in terms of oncologic safety and biological healing.
由于主要血管解剖结构复杂、从髂骨翼进行后路显露视野不清以及L5椎体相对较大,L5椎体切除术治疗脊柱肿瘤是一项技术要求较高的手术。在本研究中,我们介绍了一例孤立性脊柱转移性肾细胞癌(RCC)患者行L5椎体切除术、椎体切除及前路重建的手术技术。
一名54岁男性1年前因RCC接受了右肾全切术。术后1年随访时,CT扫描和MRI显示L5椎体孤立性转移。采用前后两阶段入路。为便于椎体切除,通过后路将横突与椎体分离。在前路基础上,经左髂总血管之间的间隙切除椎体。使用液氮冷冻的含瘤骨与自体骨混合后置于可扩张钛笼中进行重建。
未观察到术中并发症。术后,患者双侧胫骨前肌和拇长伸肌出现肌无力,但随时间推移有所改善。术后7个月,患者能够独立行走。在最近2.5年的随访中,未出现病变局部复发。植骨已与相邻椎体融合。
本报告描述了一种新的L5椎体切除术技术,该技术可便于安全切除L5椎体,并证明了液氮冷冻的含瘤骨与自体骨混合用于前路重建在肿瘤学安全性和生物愈合方面的有效性。