Babnik J, Curin V, Lah T, Turk V, Skaleric U
Department of Biochemistry, J. Stefan Institute, E. Kardelj University, Ljubljana, Yugoslavia.
Biol Chem Hoppe Seyler. 1988 May;369 Suppl:271-6.
In the present work we demonstrate the presence of cysteine proteinase inhibitors of all three classes: kininogens, stefin A, and cystatin C, in inflamed human gingiva. Using cystatin C, in inflamed human gingiva. Using immunochemical methods we found that stefin A is the major inhibitor of cysteine proteinases, followed by kininogen and cystatin C. The values for stefin A and cystatin C ranged from 7.0--400 micrograms/g and 1.5--6.1 micrograms/g tissue, respectively, as determined by enzyme-linked immunosorbent assay in inflamed gingival homogenates from patients with different degrees of periodontal disease.
