埃塞俄比亚北部提格雷地区孕妇中单核细胞增生李斯特菌的流行情况及耐药模式：一项横断面研究
Prevalence and drug resistance pattern of Listeria monocytogenes among pregnant women in Tigray region, Northern Ethiopia: a cross-sectional study.
作者信息
Welekidan Letemichael Negash, Bahta Yemane Weldu, Teklehaimanot Mebrihit Gebremeskel, Abay Getahun Kahsay, Wasihun Araya Gebreyesus, Dejene Tsehaye Asmelash, Muthupandian Saravanan, Mezgebo Tadele Araya, Hagos Amlsha Kahsay
机构信息
Department of Medical Microbiology and Immunology, Division of Biomedical Sciences, College of Health Science, Mekelle University, P.O.Box:1871, Mekelle, Tigray, Ethiopia.
Department of Obstetrics and Gynaecology, School of Medicine, College of Health Sciences, Mekelle University, P.O.Box:1871, Mekelle, Tigray, Ethiopia.
出版信息
BMC Res Notes. 2019 Aug 23;12(1):538. doi: 10.1186/s13104-019-4566-8.
OBJECTIVE
The aim of this study was to determine the prevalence and antimicrobial susceptibility test of Listeria monocytogenes among pregnant women in Tigray region, Ethiopia.
RESULTS
The overall prevalence of L. monocytogenes among pregnant women was found to be (8.5%; 12/141). With regard to the socio-demographic characteristics, a high prevalence of L. monocytogenes was observed in the age group of 20-24 years (18.6%; 8/43), rural dwellers (10%; 3/30), secondary school (9.6%; 5/52), and housewives (11.4%;10/88). A high drug resistance rate was observed to penicillin G (66.7%), clindamycin (66.7%), amoxicillin (50%) and vancomycin (50%). However, isolates were relatively sensitive to ciprofloxacin (75%), erythromycin (75%), trimethoprim/sulphamethaxazole (66.7%) and chloramphenicol (60%).
目的
本研究旨在确定埃塞俄比亚提格雷地区孕妇中单核细胞增生李斯特菌的流行率及抗菌药敏试验情况。
结果
孕妇中单核细胞增生李斯特菌的总体流行率为（8.5%；12/141）。就社会人口学特征而言，在20 - 24岁年龄组（18.6%；8/43）、农村居民（10%；3/30）、中学学历者（9.6%；5/52）以及家庭主妇（11.4%；10/88）中观察到单核细胞增生李斯特菌的高流行率。观察到对青霉素G（66.7%）、克林霉素（66.7%）、阿莫西林（50%）和万古霉素（(50%）的高耐药率。然而，分离株对环丙沙星（75%）、红霉素（75%）、甲氧苄啶/磺胺甲恶唑（66.7%）和氯霉素（60%）相对敏感。
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