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妊娠期李斯特菌病:一个公共卫生问题。

Listeriosis during Pregnancy: A Public Health Concern.

作者信息

Mateus Teresa, Silva Joana, Maia Rui L, Teixeira Paula

机构信息

Centro de Biotecnologia e Química Fina (CBQF) Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa/Porto, Rua Dr. António Bernardino Almeida, 4200-072 Porto, Portugal ; Departamento de Medicina Veterinária (EUVG), Escola Universitária Vasco da Gama, Coimbra, Portugal.

出版信息

ISRN Obstet Gynecol. 2013 Sep 26;2013:851712. doi: 10.1155/2013/851712.

Abstract

Listeria was first described in 1926 by Murray, Webb, and Swann, who discovered it while investigating an epidemic infection among laboratory rabbits and guinea pigs. The role of Listeria monocytogenes as a foodborne pathogen was definitively recognized during the 1980s. This recognition was the consequence of a number of epidemic human outbreaks due to the consumption of contaminated foods, in Canada, in the USA and in Europe. Listeriosis is especially severe in immunocompromised individuals such as pregnant women. The disease has a low incidence of infection, although this is undeniably increasing, with a high fatality rate amongst those infected. In pregnant women listeriosis may cause abortion, fetal death, or neonatal morbidity in the form of septicemia and meningitis. Improved education concerning the disease, its transmission, and prevention measures for immunocompromised individuals and pregnant women has been identified as a pressing need.

摘要

1926年,默里、韦伯和斯旺首次描述了李斯特菌,他们在调查实验室兔子和豚鼠中的流行性感染时发现了这种细菌。20世纪80年代,人们明确认识到单核细胞增生李斯特菌作为食源性病原体的作用。这种认识是由于在加拿大、美国和欧洲发生了多起因食用受污染食物导致的人类疫情爆发。李斯特菌病在免疫功能低下的个体(如孕妇)中尤为严重。尽管感染率确实在上升,但该疾病的感染发生率较低,且感染者的死亡率很高。在孕妇中,李斯特菌病可能导致流产、胎儿死亡或败血症和脑膜炎等形式的新生儿发病。人们已确定迫切需要加强对该疾病、其传播方式以及针对免疫功能低下个体和孕妇的预防措施的教育。

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