Plachouri Kerasia-Maria, Georgiou Sophia
Dermatology Department, University of Patras, Patras, Greece.
J Cosmet Dermatol. 2019 Dec;18(6):1601-1605. doi: 10.1111/jocd.13115. Epub 2019 Aug 24.
Mesotherapy is a procedure that involves the injection of active substances into the dermis and subcutaneous tissue in order to treat several local medical and cosmetic conditions. Despite being considered as a relatively safe method, a series of adverse reactions can occur due to its wide application and lack of standardization processes.
The aim of this paper is to summarize all the mesotherapy-related complications published so far, and to provide an insight into their management.
PATIENT/METHODS: Articles derived from the databases, PubMed, EMBASE, and SCOPUS, and published between 1992 and 2018, were analyzed for this review. The study was conducted according to the PRISMA guidelines.
In this literature, there is a number of case series and isolated case reports describing various side effects of different severities. The therapeutic management of these complications is-in most cases-individualized.
Larger systematic studies are needed in order to adequately evaluate the safety profile of mesotherapy, and in order to determine standardized therapy parameters, so as to minimize the risk of potential adverse reactions.
中胚层疗法是一种将活性物质注射到真皮和皮下组织以治疗多种局部医学和美容病症的方法。尽管被认为是一种相对安全的方法，但由于其广泛应用和缺乏标准化流程，仍可能发生一系列不良反应。
本文旨在总结迄今为止发表的所有与中胚层疗法相关的并发症，并深入探讨其处理方法。
患者/方法：对1992年至2018年间发表于PubMed、EMBASE和SCOPUS数据库的文章进行分析以进行本综述。该研究按照PRISMA指南进行。
在该文献中，有许多病例系列和个别病例报告描述了不同严重程度的各种副作用。这些并发症的治疗管理在大多数情况下是个体化的。
需要进行更大规模的系统研究，以充分评估中胚层疗法的安全性，并确定标准化的治疗参数，从而将潜在不良反应的风险降至最低。
