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钠和钾的排泄量预示着城市青少年抑郁症患病率的增加。

Sodium and potassium excretion predict increased depression in urban adolescents.

作者信息

Mrug Sylvie, Orihuela Catheryn, Mrug Michal, Sanders Paul W

机构信息

Department of Psychology, University of Alabama at Birmingham, Birmingham, Alabama.

Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.

出版信息

Physiol Rep. 2019 Aug;7(16):e14213. doi: 10.14814/phy2.14213.

DOI:10.14814/phy2.14213
PMID:31444870
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6708056/
Abstract

This study examined the prospective role of urinary sodium and potassium excretion in depressive symptoms among urban, low-income adolescents, and whether these relationships vary by gender. A total of 84 urban adolescents (mean age 13.36 years; 50% male; 95% African American) self-reported on their depressive symptoms at baseline and 1.5 years later. At baseline, the youth also completed a 12-h (overnight) urine collection at home which was used to measure sodium and potassium excretion. After adjusting for baseline depressive symptoms, age, BMI percentile, and pubertal development, greater sodium excretion and lower potassium excretion predicted more severe depressive symptoms at follow-up, with no significant gender differences. The results suggest that consumption of foods high in sodium and low in potassium contributes to the development of depressive symptoms in early adolescence, and that diet is a modifiable risk factor for adolescent depression. Interventions focusing on diet may improve mental health in urban adolescents.

摘要

本研究调查了尿钠和钾排泄量在城市低收入青少年抑郁症状中的前瞻性作用,以及这些关系是否因性别而异。共有84名城市青少年(平均年龄13.36岁;50%为男性;95%为非裔美国人)在基线时和1.5年后自我报告了他们的抑郁症状。在基线时,这些青少年还在家中完成了一次12小时(过夜)的尿液收集,用于测量钠和钾的排泄量。在对基线抑郁症状、年龄、BMI百分位数和青春期发育进行调整后,较高的钠排泄量和较低的钾排泄量预示着随访时更严重的抑郁症状,且无显著性别差异。结果表明,高钠低钾食物的摄入会导致青春期早期抑郁症状的出现,饮食是青少年抑郁症的一个可改变的风险因素。关注饮食的干预措施可能会改善城市青少年的心理健康。

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