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日本老年患者脊柱手术的并发症:对世界人口老龄化未来的启示。

Complications of Spine Surgery in Elderly Japanese Patients: Implications for Future of World Population Aging.

作者信息

Umekawa Motoyuki, Takai Keisuke, Taniguchi Makoto

机构信息

Department of Neurosurgery, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan.

出版信息

Neurospine. 2019 Dec;16(4):780-788. doi: 10.14245/ns.1938184.092. Epub 2019 Aug 25.

Abstract

OBJECTIVE

To analyze the relationship between age and perioperative complications of spine surgery in a Japanese cohort with the longest average life expectancy in the world.

METHODS

Patients with spinal stenosis who underwent standard spine surgery without instrumented fusion were divided into 4 groups: adults (20-64 years), the young-old (65-74), the middle old (75-84), and the oldest-old (≥85). Data on medical complications, surgical complications, and deaths within 30 days of index surgery were compared across the groups. Risk factors for complications were identified through multivariate analysis.

RESULTS

A total of 584 patients underwent 673 operations: 35% were performed on adult patients, 33% on the young-old, 27% on the middle old, and 5% on the oldest-old. The rates of total or [major] medical complications significantly increased with age (8% [0.8%], 11% [0.9%], 27% [3.9%], 45% [9.1%], respectively; p<0.001 [p=0.003]), whereas those of surgical complications did not differ (11%, 8.1%, 14%, 9.1%, respectively; p=0.25). Independent risk factors for medical complications were an age of 75 years or older (75-84: odds ratio [OR], 5.1; ≥85: OR, 6.2) and American Society of Anesthesiologists (ASA) physical status classification III (OR, 5.4). Two patients older than 85 years died from medical complications.

CONCLUSION

The complications of spine surgery increased in the middle and oldest-old patients because of medical complications; however, most were minor and treatable. Major complications were associated with preoperative medical comorbidities and their severities; therefore, most elderly patients with low ASA physical status classification (≤II) may benefit from spine surgery.

摘要

目的

分析在全球平均预期寿命最长的日本队列中,年龄与脊柱手术围手术期并发症之间的关系。

方法

将接受非器械融合标准脊柱手术的腰椎管狭窄症患者分为4组:成年人(20 - 64岁)、年轻老年人(65 - 74岁)、中年老年人(75 - 84岁)和高龄老年人(≥85岁)。比较各组在初次手术30天内的医疗并发症、手术并发症和死亡数据。通过多因素分析确定并发症的危险因素。

结果

共有584例患者接受了673次手术:35%的手术针对成年患者,33%针对年轻老年人,27%针对中年老年人,5%针对高龄老年人。总的或[主要]医疗并发症发生率随年龄显著增加(分别为8% [0.8%]、11% [0.9%]、27% [3.9%]、45% [9.1%];p<0.001 [p = 0.003]),而手术并发症发生率无差异(分别为11%、8.1%、14%、9.1%;p = 0.25)。医疗并发症的独立危险因素为75岁及以上年龄(75 - 84岁:比值比[OR],5.1;≥85岁:OR,6.2)和美国麻醉医师协会(ASA)身体状况分级III级(OR,5.4)。2例85岁以上患者死于医疗并发症。

结论

由于医疗并发症,脊柱手术并发症在中年和高龄老年患者中增加;然而,大多数为轻微且可治疗的。主要并发症与术前合并症及其严重程度相关;因此,大多数ASA身体状况分级较低(≤II级)的老年患者可能从脊柱手术中获益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da52/6944995/1fd132b7e3c4/ns-1938184-092f1.jpg

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