Sun G H, Li D W, Guo S, Zhang D M, Cui S H
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Aug;33(8):789-792. doi: 10.13201/j.issn.1001-1781.2019.08.028.
Chronic nasal-sinusitis is a chronic inflammatory disease characterized by persistent inflammation in the nasal and nasal mucosa. The pathogenesis of CRS is extremely complex and there is currently a lack of effective therapy. The reason for inaccurate diagnosis and invalid treatment of CRS is its sophisticated and unclear mechanism. The pathogenesis of CRS from Asian populations is neutrophil infiltration mediated by Th1/Th17 mixture. Consequently, exploring the function of neutrophil in the pathogenesis of CRS plays an important role in clinical diagnosis and treatment for CRS patients in China.
慢性鼻-鼻窦炎是一种慢性炎症性疾病，其特征为鼻腔和鼻黏膜持续存在炎症。慢性鼻-鼻窦炎的发病机制极其复杂，目前缺乏有效的治疗方法。慢性鼻-鼻窦炎诊断不准确和治疗无效的原因在于其机制复杂且不明确。亚洲人群慢性鼻-鼻窦炎的发病机制是由Th1/Th17混合介导的中性粒细胞浸润。因此，探讨中性粒细胞在慢性鼻-鼻窦炎发病机制中的作用，对我国慢性鼻-鼻窦炎患者的临床诊断和治疗具有重要意义。
