• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

空肠多发穿孔合并腹部伤寒和粟粒性腹膜结核

Jejunal multiple perforations for combined abdominal typhoid fever and miliary peritoneal tuberculosis.

作者信息

Grieco Michele, Polti Giorgia, Lambiase Lara, Cassini Diletta

机构信息

General Surgery Department, S Eugenio Hospital, Piazzale dell'Umanesimo 10, 00144 Rome, Rome, Italy.

Immunoinfectivology Department, Bambino Gesù Pediatric Hospital, Piazza di Sant'Onofrio 4, 00165 Rome, Rome, Italy.

出版信息

Pan Afr Med J. 2019 May 23;33:51. doi: 10.11604/pamj.2019.33.51.14664. eCollection 2019.

DOI:10.11604/pamj.2019.33.51.14664
PMID:31448014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6689839/
Abstract

Typhoid fever and tuberculosis, considered rare diseases in western countries, is still considered a notable problem of health issue in developing countries. The gastrointestinal manifestations of typhoid fever are the most common and the typhoid intestinal perforation (TIP) is considered the most dangerous complication. Abdominal localization of tuberculosis is the 6 most frequent site for extra pulmonary involvement, it can involve any part of the digestive system, including peritoneum, causing miliary peritoneal tuberculosis (MPT). This is the case report of a 4 years old girl with multiple jejunal perforations in a setting of contemporary miliary peritoneal tuberculosis and typhoid fever occurred in "Hopital Saint Jean de Dieu" in Tanguietà, north of Benin. The patient was admitted in the emergency department with an acute abdomen and suspect of intestinal perforation, in very bad clinical conditions, underwent emergency laparotomy. The finding was a multiple perforations of the jejunum in a setting of combined abdominal typhoid fever and miliary peritoneal tuberculosis. Typhoid intestinal perforations and peritoneal tuberculosis are a very rare cause of non-traumatic peritonitis in western country, but still common in developing country. Considering the modern migratory flux and the diffusion of volunteer missions all around the world, the western surgeon should know this pathological entities, and the best treatments available, well known by surgeons with experience of working in developing countries. The combination of both TIP and MPT in the same patient, is a very rare finding which can worsen the outcome of the patient itself.

摘要

伤寒热和肺结核在西方国家被视为罕见疾病,但在发展中国家仍被认为是一个显著的健康问题。伤寒热的胃肠道表现最为常见,而伤寒肠穿孔(TIP)被认为是最危险的并发症。腹部结核是肺外受累的第6个最常见部位,它可累及消化系统的任何部位,包括腹膜,导致粟粒性腹膜结核(MPT)。本文报告了一名4岁女孩的病例,她在贝宁北部坦吉埃塔的“圣若翰医院”同时发生了粟粒性腹膜结核和伤寒热,并伴有多处空肠穿孔。患者因急腹症和肠穿孔疑似被紧急送往急诊科,临床状况极差,接受了急诊剖腹手术。检查发现空肠多处穿孔,同时伴有腹部伤寒热和粟粒性腹膜结核。在西方国家,伤寒肠穿孔和腹膜结核是导致非创伤性腹膜炎的非常罕见的原因,但在发展中国家仍然很常见。考虑到现代移民潮和世界各地志愿者任务的传播,西方外科医生应该了解这些病理实体以及现有的最佳治疗方法,这些方法为有在发展中国家工作经验的外科医生所熟知。同一患者同时出现TIP和MPT是非常罕见的情况,这可能会使患者的病情恶化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7828/6689839/a38aa7243d80/PAMJ-33-51-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7828/6689839/428c9a546a59/PAMJ-33-51-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7828/6689839/a38aa7243d80/PAMJ-33-51-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7828/6689839/428c9a546a59/PAMJ-33-51-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7828/6689839/a38aa7243d80/PAMJ-33-51-g002.jpg

相似文献

1
Jejunal multiple perforations for combined abdominal typhoid fever and miliary peritoneal tuberculosis.空肠多发穿孔合并腹部伤寒和粟粒性腹膜结核
Pan Afr Med J. 2019 May 23;33:51. doi: 10.11604/pamj.2019.33.51.14664. eCollection 2019.
2
Multiple jejunoileal perforations because of intestinal involvement of miliary tuberculosis in an infant.一名婴儿因粟粒性肺结核累及肠道导致多发空肠回肠穿孔。
J Pediatr Surg. 2008 Sep;43(9):e17-21. doi: 10.1016/j.jpedsurg.2008.03.063.
3
Typhoid Fever Presenting with Ileal Perforation and Gastric Perforation.伤寒并发回肠穿孔和胃穿孔。
West Afr J Med. 2024 Jan 31;41(1):92-96.
4
A contemporary evaluation of enteric perforations in typhoid fever: analysis of 257 cases.伤寒热肠穿孔的当代评估:257例病例分析
Int Surg. 1990 Apr-Jun;75(2):96-100.
5
Colonic perforations in enteric fever.伤寒中的结肠穿孔
J Coll Physicians Surg Pak. 2004 Oct;14(10):634-5. doi: 10.2004/JCPSP.634635.
6
Intestinal perforation due to miliary tuberculosis in a patient with Behcet's disease.白塞病患者并发粟粒性肺结核致肠穿孔
Mt Sinai J Med. 2006 Sep;73(5):825-7.
7
Comparative analysis of primary repair vs resection and anastomosis, with laparostomy, in management of typhoid intestinal perforation: results of a rural hospital in northwestern Benin.在贝宁西北部的一家农村医院中,对原发性修复与切除和吻合术(加剖腹术)治疗伤寒肠穿孔的效果进行对比分析。
BMC Gastroenterol. 2013 Jun 19;13:102. doi: 10.1186/1471-230X-13-102.
8
[Abdominal tuberculosis--a surgical reality].[腹部结核——外科实际情况]
Chirurgia (Bucur). 2007 May-Jun;102(3):303-8.
9
Operative management of typhoid ileal perforation in children.儿童伤寒性回肠穿孔的手术治疗
Afr J Paediatr Surg. 2010 Jan-Apr;7(1):9-13. doi: 10.4103/0189-6725.59351.
10
Typhoid colonic perforation in childhood: a ten-year experience.儿童期伤寒性结肠穿孔:十年经验
World J Surg. 2006 Feb;30(2):242-7. doi: 10.1007/s00268-005-0148-0.

引用本文的文献

1
Abdominal tuberculosis in children: a systematic review on current advances.儿童腹部结核病:当前进展的系统评价
Pediatr Surg Int. 2025 Jun 18;41(1):175. doi: 10.1007/s00383-025-06080-0.
2
Uncommon ileal perforation due to intestinal tuberculosis: A case report and literature review.肠结核所致罕见回肠穿孔:一例报告及文献复习
Medicine (Baltimore). 2025 Jan 3;104(1):e41099. doi: 10.1097/MD.0000000000041099.
3
Supradiaphragmatic Jejunal Perforation Following Total Gastrectomy With Esophagojejunostomy Reconstruction for Gastric Adenocarcinoma.

本文引用的文献

1
Immunopathogenesis of granulomas in chronic autoinflammatory diseases.慢性自身炎症性疾病中肉芽肿的免疫发病机制。
Clin Transl Immunology. 2016 Dec 16;5(12):e118. doi: 10.1038/cti.2016.75. eCollection 2016 Dec.
2
Systematic review of the global epidemiology, clinical and laboratory profile of enteric fever.伤寒全球流行病学、临床及实验室特征的系统评价
J Glob Health. 2015 Dec;5(2):020407. doi: 10.7189/jogh.05.020407.
3
Comparison of Outcomes between Early Fascial Closure and Delayed Abdominal Closure in Patients with Open Abdomen: A Systematic Review and Meta-Analysis.
胃腺癌全胃切除食管空肠吻合重建术后膈上空肠穿孔
Cureus. 2024 Apr 19;16(4):e58587. doi: 10.7759/cureus.58587. eCollection 2024 Apr.
早期筋膜闭合与延迟腹部闭合治疗开放性腹部患者结局的比较:系统评价和荟萃分析。
Gastroenterol Res Pract. 2014;2014:784056. doi: 10.1155/2014/784056. Epub 2014 Jun 2.
4
Comparative analysis of primary repair vs resection and anastomosis, with laparostomy, in management of typhoid intestinal perforation: results of a rural hospital in northwestern Benin.在贝宁西北部的一家农村医院中,对原发性修复与切除和吻合术(加剖腹术)治疗伤寒肠穿孔的效果进行对比分析。
BMC Gastroenterol. 2013 Jun 19;13:102. doi: 10.1186/1471-230X-13-102.
5
Typhoid fever and paratyphoid fever: Systematic review to estimate global morbidity and mortality for 2010.伤寒和副伤寒:系统评价估计 2010 年全球发病率和死亡率。
J Glob Health. 2012 Jun;2(1):010401. doi: 10.7189/jogh.02.010401.
6
Risk adjustment is crucial in comparing outcomes of various surgical modalities in patients with ileal perforation.在比较回肠穿孔患者不同手术方式的结果时,风险调整至关重要。
Patient Saf Surg. 2008 Nov 24;2(1):31. doi: 10.1186/1754-9493-2-31.
7
Prognostic factors in typhoid ileal perforation: a prospective study of 53 cases.伤寒性回肠穿孔的预后因素:53例前瞻性研究
J Natl Med Assoc. 2007 Sep;99(9):1042-5.
8
Typhoid intestinal perforations: twenty-six year experience.伤寒性肠穿孔:26年的经验
World J Surg. 2007 Sep;31(9):1883-1888. doi: 10.1007/s00268-007-9141-0.
9
Diagnosis of abdominal tuberculosis: experience from 11 cases and review of the literature.腹部结核的诊断:11例经验及文献复习
World J Gastroenterol. 2004 Dec 15;10(24):3647-9. doi: 10.3748/wjg.v10.i24.3647.
10
The global burden of typhoid fever.伤寒热的全球负担。
Bull World Health Organ. 2004 May;82(5):346-53.