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从近乎成熟的 果实中分离得到两个新的喹诺酮生物碱。

Two new quinolone alkaloids from the nearly ripe fruits of .

机构信息

Jiangsu Key Laboratory for the Research and Utilization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, People's Republic of China.

The Jiangsu Provincial Platform for Conservation and Utilization of Agricultural Germplasm, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, People's Republic of China.

出版信息

Nat Prod Res. 2020 Jul;34(13):1868-1873. doi: 10.1080/14786419.2019.1566819. Epub 2019 Aug 26.

Abstract

(Juss.) Benth. belong to the family of Rutaceae. The complete and nearly ripe fruits of is used as traditional Chinese medicine and phytochemical investigations have been conducted on extracts of the seeds of to provide scientific validation of its properties. In this study, we successfully isolated two new quinolone alkaloids (-) from the MeOH extractive of nearly ripe fruits of . The structure elucidation of these compounds was determined by one- and two-dimensional nuclear magnetic resonance, ultraviolet and electrospray ionisation time-of-flight mass spectrometry. This finding expands the understanding of the natural constituents of the Rutaceae, in particular, the genera.

摘要

(Juss.)Benth. 属于芸香科。 作为传统中药使用的是完全成熟和近成熟的果实,对 的种子提取物进行了植物化学研究,为其特性提供了科学依据。在这项研究中,我们成功地从近成熟的果实的甲醇提取物中分离出两种新的喹诺酮生物碱(-)。通过一维和二维核磁共振、紫外和电喷雾离子化飞行时间质谱对这些化合物的结构进行了确定。这一发现扩展了对芸香科,特别是 属的天然成分的认识。

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