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喉全切除术后患者非计划性再入院的风险因素。

Risk factors for unplanned readmission in total laryngectomy patients.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, U.S.A.

Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, U.S.A.

出版信息

Laryngoscope. 2020 Jul;130(7):1725-1732. doi: 10.1002/lary.28255. Epub 2019 Aug 26.

Abstract

OBJECTIVE

To determine which patient or surgical factors affect the likelihood of unplanned readmission (within 30 days) after total laryngectomy (TL).

METHODS

Retrospective chart review of all patients who underwent TL at a single institution from April 2007 through August 2016. Primary outcome was unplanned readmission to the hospital within 30 days of discharge. Univariable and multivariable logistic regression were performed to identify risk factors for unplanned readmission.

RESULTS

Two hundred seventy-eight patients met inclusion criteria. Twenty-nine patients (10.4%) had unplanned readmissions within 30 days. The most common reasons for readmission were pharyngocutaneous fistula (n = 15), neck abscess (n = 3), and wound breakdown (n = 4). Average time to unplanned readmission was 11.2 days (range 0-27 days). Fistula (OR 30.259; 95% CI, 9.186, 118.147; P ≤ .001), postoperative pneumonia (OR 9.491; 95% CI, 1.783, 53.015; P = .008), and history of cardiac disease (OR 7.074; 95% CI, 2.324, 25.088, P = .001) were independently associated with an increased risk of 30-day unplanned readmission on multivariate analysis. However, return to OR on initial admission was associated with a lower risk of unplanned readmission (OR 0.075; 95% CI, 0.009, 0.402; P = .007). Unplanned readmission was associated with a delay in initiation of adjuvant radiation (OR 1.494; 95% CI, 1.397, 1.599; P < .001).

CONCLUSION

Unplanned readmission occurs in a small but significant number of TL patients. Patients who have a 30-day unplanned readmission may be at risk for a delay in initiation of adjuvant therapy.

LEVEL OF EVIDENCE

4 Laryngoscope, 130:1725-1732, 2020.

摘要

目的

确定哪些患者或手术因素会影响喉全切除术(TL)后 30 天内(30 天内)计划外再入院的可能性。

方法

对 2007 年 4 月至 2016 年 8 月期间在一家机构接受 TL 的所有患者进行回顾性图表审查。主要结果是出院后 30 天内计划外再次入院到医院。采用单变量和多变量逻辑回归分析确定计划外再入院的危险因素。

结果

符合纳入标准的 278 例患者。29 例(10.4%)在 30 天内计划外再入院。再入院的最常见原因是咽皮瘘(n=15)、颈部脓肿(n=3)和伤口破裂(n=4)。计划外再入院的平均时间为 11.2 天(范围 0-27 天)。瘘管(OR 30.259;95%CI,9.186,118.147;P≤.001)、术后肺炎(OR 9.491;95%CI,1.783,53.015;P=.008)和心脏病史(OR 7.074;95%CI,2.324,25.088,P=.001)是 30 天内计划外再入院的独立危险因素。然而,初次入院返回手术室与计划外再入院风险降低相关(OR 0.075;95%CI,0.009,0.402;P=0.007)。计划外再入院与辅助放疗开始时间延迟相关(OR 1.494;95%CI,1.397,1.599;P<.001)。

结论

TL 患者中有一小部分但数量可观的患者会出现计划外再入院。30 天内计划外再入院的患者可能有辅助治疗开始延迟的风险。

证据水平

4 级喉镜,130:1725-1732,2020。

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