School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
School of Wushu, Wuhan Sport University, Wuhan, China.
J Altern Complement Med. 2019 Oct;25(10):1005-1008. doi: 10.1089/acm.2019.0050. Epub 2019 Aug 26.
The aim of this pilot study was to assess the effects of a program on health-related quality of life (HR-QOL) in centrally obese adults with depression. Two hundred thirteen participants were randomly allocated to either a intervention group ( = 106) or a usual medical care control group ( = 107). The group involved 3 × 1.5 h supervised and group-based training sessions per week for 24 weeks. Indicators of HR-QOL were assessed by questionnaire at baseline, 12 weeks, and 24 weeks. There were significant improvements in favor of the group for the SF-36 subscales of physical functioning ( < 0.01), role physical ( < 0.01), and role emotional ( < 0.01) at 12 and 24 weeks. Scores for bodily pain were improved in the control group at 12 weeks ( < 0.01) and 24 weeks ( < 0.05), but not in the group. There was also a significant improvement in favor of the control group in general health ( < 0.05) at 12 weeks, but not at 24 weeks. A further analysis showed clinically significant changes in favor of the group in physical functioning ( < 0.05 or = 0.05), role physical ( < 0.05), and role emotional ( < 0.05), and in favor of the control group in bodily pain ( < 0.05) at 12 and 24 weeks. The findings show that exercise improved indicators of HR-QOL including physical functioning, role physical, and role emotional in centrally obese adults with depression.
本研究旨在评估一项方案对伴发抑郁的中心性肥胖成年人健康相关生活质量(HR-QOL)的影响。213 名参与者被随机分配至干预组(n=106)或常规医疗照护对照组(n=107)。干预组包括每周 3 次、每次 1.5 小时的监督性团体训练,共 24 周。使用问卷于基线、12 周和 24 周评估 HR-QOL 指标。与对照组相比,干预组 SF-36 量表的生理机能( < 0.01)、生理职能( < 0.01)和情感职能( < 0.01)在 12 周和 24 周时均显著改善。对照组在 12 周( < 0.01)和 24 周( < 0.05)时躯体疼痛评分改善,但干预组无此变化。对照组在 12 周时一般健康状况显著改善( < 0.05),但在 24 周时无此变化。进一步分析显示,与对照组相比,干预组在生理机能( < 0.05 或 = 0.05)、生理职能( < 0.05)和情感职能( < 0.05)方面具有更优的临床改善,而对照组在躯体疼痛方面( < 0.05)在 12 周和 24 周时具有更优的改善。研究结果表明,运动改善了伴发抑郁的中心性肥胖成年人的 HR-QOL 指标,包括生理机能、生理职能和情感职能。