Mertl C, Isorni C, Rey J L, Choquet D, Duboisset M, Lesbre J P
Service de cardiologie B, CHRU, hôpital Sud, Amiens.
Arch Mal Coeur Vaiss. 1988 Jun;81(6):735-42.
The purpose of this study, performed in 80 patients with aortic valve stenosis, was to find out whether continuous wave doppler ultrasound was reliable in assessing the severity of the stenosis. Maximum mean and instantaneous transaortic pressure gradients obtained by continuous wave doppler were compared with maximum mean instantaneous and peak to peak gradients simultaneously obtained by cardiac catheterization. 35 patients who underwent aortic valve dilation were explored beforehand and afterwards, which brings up to 115 the total number of gradient comparisons. There was a correlation between maximum instantaneous gradient at doppler and peak to peak gradient (r = 0.62, n = 115, e = 22.5 mmHg, p less than 0.001). A similar correlation was found between maximum instantaneous gradients at doppler and haemodynamics (r = 0.64, n = 80, e = 24.5 mmHg), but correlation between mean gradients was weaker (r = 0.57, n = 80, e = 17.7 mmHg). Maximum and mean instantaneous gradients are underestimated by the doppler method. After exclusion of imperfect doppler curves, correlations were better, notably as regards mean gradients (r = 0.80, n = 18, e = 11.9 mmHg). There was a closer correlation between doppler maximum instantaneous gradients and haemodynamic peak to peak gradients in patients without aortic regurgitation (r = 0.71, n = 45, e = 17.2 mmHg) than in patients with aortic regurgitation (r = 0.54, n = 70, e = 24.3 mmHg).(ABSTRACT TRUNCATED AT 250 WORDS)
本研究对80例主动脉瓣狭窄患者进行,目的是探究连续波多普勒超声在评估狭窄严重程度方面是否可靠。将连续波多普勒获得的最大平均及瞬时跨主动脉压力阶差与心导管检查同时获得的最大平均瞬时及峰-峰阶差进行比较。对35例行主动脉瓣扩张术的患者在术前和术后进行了检查,使得阶差比较总数达到115次。多普勒测量的最大瞬时阶差与峰-峰阶差之间存在相关性(r = 0.62,n = 115,e = 22.5 mmHg,p < 0.001)。在多普勒测量的最大瞬时阶差与血流动力学之间也发现了类似的相关性(r = 0.64,n = 80,e = 24.5 mmHg),但平均阶差之间的相关性较弱(r = 0.57,n = 80,e = 17.7 mmHg)。多普勒方法会低估最大和平均瞬时阶差。排除不完美的多普勒曲线后,相关性更好,尤其是平均阶差方面(r = 0.80,n = 18,e = 11.9 mmHg)。在无主动脉瓣反流的患者中,多普勒最大瞬时阶差与血流动力学峰-峰阶差之间的相关性(r = 0.71,n = 45,e = 17.2 mmHg)比有主动脉瓣反流的患者(r = 0.54,n = 70,e = 24.3 mmHg)更密切。(摘要截短于250字)