Suppr超能文献

[通过多普勒技术评估主动脉瓣狭窄的严重程度]

[Severity of aortic stenosis assessed by Doppler techniques].

作者信息

Nakamura K, Shiina T, Satomi G, Sakai K, Tamura K, Matsumura K, Umemura J, Magosaki N, Koyanagi H, Hirosawa K

机构信息

Heart Institute of Japan, Tokyo Women's Medical College.

出版信息

J Cardiol. 1987 Dec;17(4):807-16.

PMID:3333519
Abstract

Continuous wave (CW) Doppler ultrasound has facilitated accurate estimates of pressure gradient (PG) across a stenotic valve. However, the severity of stenosis cannot be assessed using PG alone because it is dependent on actual flow across the valve. In this study, Doppler techniques were used to predict PG and aortic valve areas (AVA) in adults with aortic stenosis (AS). Fifty-four adult patients undergoing cardiac catheterization for suspected AS were prospectively evaluated. There were 28 men and 26 women, who ranged in age from 25 to 68 years with a mean of 56 years. These Doppler ultrasound studies were performed using a 2 MHz transducer and an Aloka SSD-730. With CW Doppler ultrasound, the highest velocities of the aortic jet were recorded from an apical approach. Left ventricular outflow flows were recorded about 1.0-1.5 cm below the aortic annulus using high PRF. Doppler waveforms were analyzed for the AT/ET (AT: acceleration time, ET: ejection time), and Doppler PG was calculated from the maximum velocity (V) of the aortic jet based on a modified Bernoulli equation (PG = 4V2), and aortic valve area was obtained using the continuity equation-(AVA = left ventricular outflow tract stroke volume divided by AS jet velocity integral). These data were compared with hemodynamic data obtained from cardiac catheterization. The following results were obtained: 1. In eight patients with substantial aortic regurgitation, whose maximum catheter PG were from 20 to 45 mmHg, the AT/ET was less than 0.30. The ratio of AT/ET correlated with the peak velocity of the aortic jet (r = 0.88) and the maximum PG (r = 0.87) obtained from cardiac catheterization. 2. In 46 patients with AS, the maximum PG by CW Doppler showed an excellent correlation with maximum catheterization PG (r = 0.97, SEE 6 mmHg), and the mean PG as calculated by the two techniques also disclosed a good correlation (r = 0.97, SEE 5.4 mmHg).(ABSTRACT TRUNCATED AT 400 WORDS)

摘要

连续波(CW)多普勒超声有助于准确估计跨狭窄瓣膜的压力阶差(PG)。然而,仅使用PG无法评估狭窄的严重程度,因为它取决于跨瓣膜的实际血流量。在本研究中,采用多普勒技术预测成人主动脉瓣狭窄(AS)患者的PG和主动脉瓣面积(AVA)。对54例因疑似AS而接受心导管检查的成年患者进行了前瞻性评估。其中男性28例,女性26例,年龄在25至68岁之间,平均年龄56岁。这些多普勒超声检查使用2MHz探头和Aloka SSD - 730进行。采用CW多普勒超声,从心尖途径记录主动脉射流的最高速度。使用高脉冲重复频率(PRF)在主动脉瓣环下方约1.0 - 1.5cm处记录左心室流出道血流。分析多普勒波形的加速时间(AT)/射血时间(ET),并根据修正的伯努利方程(PG = 4V²)从主动脉射流的最大速度(V)计算多普勒PG,使用连续性方程获得主动脉瓣面积(AVA = 左心室流出道每搏量除以主动脉瓣狭窄射流速度积分)。将这些数据与心导管检查获得的血流动力学数据进行比较。得到以下结果:1. 在8例存在大量主动脉瓣反流的患者中,其心导管检查的最大PG为20至45mmHg,AT/ET小于0.30。AT/ET比值与心导管检查获得的主动脉射流峰值速度(r = 0.88)和最大PG(r = 0.87)相关。2. 在46例AS患者中,CW多普勒测得的最大PG与心导管检查的最大PG显示出极好的相关性(r = 0.97,标准误6mmHg),两种技术计算的平均PG也显示出良好的相关性(r = 0.97,标准误5.4mmHg)。(摘要截断于400字)

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验