Research Center of Mathematics for Social Creativity, Research Institute for Electronic Science, Hokkaido University, N20W10, Sapporo, 001-0020, Japan; Institute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University, N21W10, Sapporo, 001-0021, Japan.
Research Center of Mathematics for Social Creativity, Research Institute for Electronic Science, Hokkaido University, N20W10, Sapporo, 001-0020, Japan; Global Station for Soft Matter, Global Institution for Collaborative Research and Education, Hokkaido University, Sapporo, 001-0021, Japan.
Curr Opin Genet Dev. 2019 Aug;57:78-83. doi: 10.1016/j.gde.2019.06.012. Epub 2019 Aug 24.
Single-celled organisms show a fascinating faculty for integrating spatial information and adapting their behaviour accordingly. As such they are of potential interest for elucidating fundamental mechanisms of developmental biology. In this mini-review we highlight current research on two organisms, the true slime mould Physarum polycephalum and the ciliates Paramecium and Tetrahymena. For each of these, we present a case study how applying physical principles to explain behaviour can lead to the understanding of general principles possibly relevant to developmental biology.
单细胞生物表现出一种令人着迷的能力，能够整合空间信息并相应地调整其行为。因此，它们对于阐明发育生物学的基本机制具有潜在的意义。在这篇迷你综述中，我们重点介绍了两种生物体的当前研究，即真黏菌 Physarum polycephalum 和纤毛虫 Paramecium 和 Tetrahymena。对于每一种生物体，我们都提出了一个案例研究，说明如何应用物理原理来解释行为可以导致对可能与发育生物学相关的一般原理的理解。
