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放松训练的悖论:广泛性焦虑障碍和重性抑郁症中放松诱导的焦虑及负性对比敏感的中介作用。

The paradox of relaxation training: Relaxation induced anxiety and mediation effects of negative contrast sensitivity in generalized anxiety disorder and major depressive disorder.

机构信息

Department of Psychology, The Pennsylvania State University, University Park, PA 16802, United States.

Department of Psychology, The Pennsylvania State University, University Park, PA 16802, United States.

出版信息

J Affect Disord. 2019 Dec 1;259:271-278. doi: 10.1016/j.jad.2019.08.045. Epub 2019 Aug 19.

Abstract

BACKGROUND

The Contrast Avoidance Model postulates that individuals with generalized anxiety disorder (GAD) fear a sharp spike in negative emotion, and thus, prefer to worry to maintain their negative affect rather than being in a more euthymic state, such as relaxation. Relaxation induced anxiety (RIA) is a paradoxical phenomenon wherein people experience a spike in their anxiety during relaxation training. Because these phenomena may be related and may also operate among individuals with major depressive disorder (MDD), we attempted to test whether negative contrast sensitivity was a mediator of GAD or MDD in the prediction of RIA.

METHODS

Individuals with GAD (n = 32), MDD (n = 34), and healthy controls (n = 30) were exposed to a negative emotional contrast by engaging with relaxation practice and then watching a negative emotional video. This was followed by the assessment of their negative contrast sensitivity. After this, participants engaged again with relaxation and RIA was measured. We examined mediation effects of negative contrast on the relationship between diagnostic status and RIA.

RESULTS

Negative contrast sensitivity fully mediated GAD and partially mediated MDD in predicting RIA.

CONCLUSIONS

Our findings support the hypotheses that negative contrast sensitivity is the mediator of both GAD and MDD in predicting RIA. This may have implications for assessment and treatment of GAD and MDD.

摘要

背景

对比回避模型假定,广泛性焦虑障碍(GAD)患者害怕负性情绪急剧增加,因此,他们宁愿担忧以维持负性情绪,而不是处于更为平静的状态,如放松状态。放松诱导的焦虑(RIA)是一种矛盾现象,即在放松训练期间,人们的焦虑会突然增加。由于这些现象可能相关,并且也可能在重度抑郁症(MDD)患者中发生,因此我们试图测试负面对比敏感度是否是预测 RIA 的 GAD 或 MDD 的中介因素。

方法

将 GAD 患者(n=32)、MDD 患者(n=34)和健康对照组(n=30)暴露于负面情绪对比中,方法是进行放松练习,然后观看负面情绪视频。之后,评估他们的负面对比敏感度。然后,参与者再次进行放松练习,测量 RIA。我们检验了负性对比在诊断状态与 RIA 之间的关系中的中介作用。

结果

负性对比敏感度完全中介了 GAD,部分中介了 MDD 对 RIA 的预测作用。

结论

我们的研究结果支持以下假设,即负面对比敏感度是预测 RIA 的 GAD 和 MDD 的中介因素。这可能对 GAD 和 MDD 的评估和治疗具有意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5a8/7288612/f68d084571a8/nihms-1592664-f0001.jpg

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