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1
Anticoagulant drugs in the elderly: the risks usually outweight the benefits.老年人使用抗凝药物：风险通常大于益处。
BMJ. 1988 Nov 12;297(6658):1261, 1263. doi: 10.1136/bmj.297.6658.1261.
2
Anticoagulant treatment of venous thromboembolism.
Surg Annu. 1972;4:151-63.
3
Anticoagulant therapy: a critique.
Am Fam Physician. 1971 Jun;3(6):87-91.
4
[Coumarin necrosis].
Schweiz Med Wochenschr. 1969 Jul 26;99(30):1069-77.
5
Anticoagulant therapy--1974.
JAMA. 1974 May 6;228(6):757-61. doi: 10.1001/jama.228.6.757.
6
[Indications for and hazards of anticoagulant therapy].
Schweiz Med Wochenschr. 1970 Apr 18;100(16):686-91.
7
Relapses of thromboembolic disease after discontinued anticoagulant therapy. A comparison of the incidence after abrupt and after gradual termination of treatment.
Am J Cardiol. 1967 Nov;20(5):670-3. doi: 10.1016/0002-9149(67)90010-0.
8
Risks of long-term oral anticoagulant therapy in elderly patients after myocardial infarction. Second report of the Sixty Plus Reinfarction Study Research Group.
Lancet. 1982 Jan 9;1(8263):64-8.
9
[Long-term anticoagulant therapy for transient ischemic attack and cerebral infarct with minor symptoms].
Lakartidningen. 1977 Nov 9;74(45):3973-8.
10
Oral anticoagulant treatment with and without aspirin.
Thromb Haemost. 1995 Jul;74(1):506-10.

引用本文的文献

1
Risk-benefit analysis: from a logical point of view.风险效益分析：从逻辑角度看。
J Bioeth Inq. 2012 Jun;9(2):161-70. doi: 10.1007/s11673-012-9366-y. Epub 2012 Mar 21.
2
Effect of age upon the induction and maintenance of anticoagulation with warfarin.年龄对华法林抗凝诱导及维持的影响。
Postgrad Med J. 1995 Mar;71(833):153-5. doi: 10.1136/pgmj.71.833.153.
3
Adverse drug reactions. An overview of special considerations in the management of the elderly patient.药物不良反应。老年患者管理中的特殊注意事项概述。
Drug Saf. 1990 Nov-Dec;5(6):421-35. doi: 10.2165/00002018-199005060-00003.
4
Adverse reactions as a cause of hospital admission in the aged.
Drugs Aging. 1992 Jul-Aug;2(4):356-67. doi: 10.2165/00002512-199202040-00008.
5
Anticoagulant treatment as a risk factor for primary intracerebral haemorrhage.抗凝治疗作为原发性脑出血的一个危险因素。
J Neurol Neurosurg Psychiatry. 1992 Dec;55(12):1121-4. doi: 10.1136/jnnp.55.12.1121.
6
Safety of anticoagulation in the elderly: reasons for discontinuing therapy.老年人抗凝治疗的安全性：治疗中断的原因
Postgrad Med J. 1992 Oct;68(804):824-8. doi: 10.1136/pgmj.68.804.824.
7
Factors affecting the precision of warfarin treatment.影响华法林治疗精准度的因素。
J Clin Pathol. 1992 Nov;45(11):1003-6. doi: 10.1136/jcp.45.11.1003.

本文引用的文献

1
Value of anticoagulants in the treatment of pulmonary embolism: a discussion paper.抗凝剂在肺栓塞治疗中的价值：一篇讨论文章。
J R Soc Med. 1981 Sep;74(9):675-81. doi: 10.1177/014107688107400911.
2
Heparin therapy in venous thromboembolism.
Am J Med. 1981 Apr;70(4):808-16. doi: 10.1016/0002-9343(81)90537-4.
3
Heparin treatment of deep vein thrombosis. Effects and complications after continuous or intermittent heparin administration.
Acta Med Scand. 1981;210(5):357-61.
4
Diagnosis and treatment of venous thromboembolism by consultants in Scotland.苏格兰顾问医生对静脉血栓栓塞症的诊断与治疗
Br Med J (Clin Res Ed). 1982;285(6342):630-2. doi: 10.1136/bmj.285.6342.630.
5
Effects of carbon dioxide, Nd-YAG, and argon laser radiation on coronary atheromatous plaques.二氧化碳、钕钇铝石榴石和氩激光辐射对冠状动脉粥样斑块的影响。
Am J Cardiol. 1982 Dec;50(6):1199-205. doi: 10.1016/0002-9149(82)90448-9.
6
Management of pulmonary embolism.肺栓塞的管理
Br Med J (Clin Res Ed). 1982 Sep 25;285(6345):831-3. doi: 10.1136/bmj.285.6345.831.
7
Different intensities of oral anticoagulant therapy in the treatment of proximal-vein thrombosis.不同强度的口服抗凝治疗在近端静脉血栓形成治疗中的应用
N Engl J Med. 1982 Dec 30;307(27):1676-81. doi: 10.1056/NEJM198212303072704.
8
The risk of intracerebral hemorrhage during oral anticoagulant treatment: a population study.口服抗凝治疗期间脑出血的风险：一项人群研究。
Ann Neurol. 1984 Nov;16(5):553-8. doi: 10.1002/ana.410160505.
9
Impact of venography on the diagnosis and management of deep vein thrombosis.静脉造影术对深静脉血栓形成诊断和处理的影响
Br Med J (Clin Res Ed). 1983 Feb 26;286(6366):698-9. doi: 10.1136/bmj.286.6366.698.
10
Bleeding associated with antithrombotic therapy.
Semin Hematol. 1980 Oct;17(4):259-91.

Anticoagulant drugs in the elderly: the risks usually outweight the benefits.

作者信息

Scott P J

机构信息

Department of Geriatric Medicine, Stobhill Hospital, Glasgow.

出版信息

BMJ. 1988 Nov 12;297(6658):1261, 1263. doi: 10.1136/bmj.297.6658.1261.

DOI:10.1136/bmj.297.6658.1261
PMID:3145076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1834741/
Abstract
摘要