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药师参与改善下消化道手术患者的结局:一项前瞻性前后对照研究。

Pharmacist involvement to improve patient outcomes in lower gastrointestinal surgery: a prospective before and after study.

机构信息

Pharmacy Department, Manchester University NHS Foundation Trust, Oxford Road, Manchester, M13 9WL, UK.

出版信息

Int J Clin Pharm. 2019 Oct;41(5):1220-1226. doi: 10.1007/s11096-019-00888-2. Epub 2019 Aug 26.

DOI:10.1007/s11096-019-00888-2
PMID:31452072
Abstract

Background Enhanced recovery pathways were first introduced in the UK in 2002 (Enhanced Recovery Partnership Programme in Delivering enhanced recovery-helping patients to get better sooner after surgery. Department of Health, London, 2010). The aims of such pathways are to reduce patient length of stay whilst still providing high quality of care. Objectives To evaluate the impact of pharmacist involvement in enhanced recovery pathways. Setting A large 1200 bed tertiary hospital in the North of England. Methods The pre-post study included all patients admitted for major colorectal surgery during the period 2013-2016. Baseline data were collected on all patients seen pre-operatively in a nurse-led pre-admission clinic. The intervention was introduced where a dedicated surgical pharmacist pre-operatively reviewed patients from the time they were listed for surgery until discharge with a focus on medicines optimisation. Main outcome measure The primary outcome measures were length of stay along with the type and number of post-operative complications. Results 100 patients were included in this study, with 50 patients in the baseline group and 50 patients in the intervention group. There was a significant reduction in the median length of stay (baseline group-10.5 days; intervention group-7.5 days; P < 0.001). The total number of complications was also less in the intervention group (baseline group-125; intervention group-75; P > 0.05) as was the number of patients whom had no complications (P > 0.05). Conclusions Active pharmacist involvement in enhanced recovery protocols is associated with a significantly reduced median length of stay as well as an overall reduction in the total number of post-operative complications.

摘要

背景

增强康复途径于 2002 年在英国首次引入(在提供增强康复方面的合作伙伴计划-帮助患者在手术后更快地康复。伦敦卫生部,2010 年)。这些途径的目的是减少患者的住院时间,同时提供高质量的护理。目的:评估药剂师参与增强康复途径的影响。地点:英格兰北部的一家大型 1200 床位的三级医院。方法:该前瞻性研究包括 2013 年至 2016 年期间所有接受主要结肠直肠手术的患者。基线数据收集了所有在术前护士主导的预入院诊所就诊的患者。干预措施是引入一名专门的外科药剂师,从患者被列入手术名单到出院,对患者进行术前评估,重点是优化药物治疗。主要观察指标:主要观察指标是住院时间以及术后并发症的类型和数量。结果:这项研究纳入了 100 名患者,其中 50 名患者为基线组,50 名患者为干预组。与基线组(中位数 10.5 天;干预组 7.5 天;P < 0.001)相比,中位住院时间显著缩短。干预组的总并发症数量也较少(基线组 125 例;干预组 75 例;P > 0.05),无并发症的患者数量也较少(P > 0.05)。结论:积极参与增强康复方案的药剂师与显著缩短的中位数住院时间以及术后总并发症数量的整体减少有关。

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BMJ Open Qual. 2017 Oct 25;6(2):e000158. doi: 10.1136/bmjoq-2017-000158. eCollection 2017.
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Medication reconciliation.用药核对
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External validation of the Revised Cardiac Risk Index and update of its renal variable to predict 30-day risk of major cardiac complications after non-cardiac surgery: rationale and plan for analyses of the VISION study.
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Saudi Pharm J. 2022 Oct;30(10):1448-1453. doi: 10.1016/j.jsps.2022.07.005. Epub 2022 Jul 25.
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Positive Patient Postoperative Outcomes with Pharmacotherapy: A Narrative Review including Perioperative-Specialty Pharmacist Interviews.药物治疗实现患者术后良好结局:一项包括围手术期专科药师访谈的叙述性综述
J Clin Med. 2022 Sep 24;11(19):5628. doi: 10.3390/jcm11195628.
修订心脏风险指数的外部验证及其肾脏变量更新以预测非心脏手术后30天主要心脏并发症风险:VISION研究的分析原理与计划
BMJ Open. 2017 Jan 9;7(1):e013510. doi: 10.1136/bmjopen-2016-013510.
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Safe management of ileostomates with high-output stomas.高输出造口回肠造口患者的安全管理。
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