Kasenda Stephen, Mategula Donnie, Chiphangwi Noel, Gadama Luis Aaron, Masamba Leo Peter Lockie
Blantyre District Health Office, Blantyre, Malawi.
Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
Malawi Med J. 2019 Jun;31(2):155-158. doi: 10.4314/mmj.v31i2.9.
Wilms' tumour is the most common renal neoplasm in children with an incidence of 10 cases per 1 million children and a median age at diagnosis of 3.5 years. In Western countries its occurrence in adults is 0.2 cases per million people in western countries and carries a poorer prognosis. The co-existence of Adult Wilms' tumour and pregnancy is extremely rare with less than 20 cases published in the English literature. We present a case of a Malawian woman who had progressive high-risk metastatic Adult Wilms' tumour in pregnancy after nephrectomy, radiotherapy and two lines of chemotherapy.
肾母细胞瘤是儿童最常见的肾脏肿瘤，发病率为每100万儿童中有10例，诊断时的中位年龄为3.5岁。在西方国家，其在成人中的发病率为每百万人0.2例，预后较差。成人肾母细胞瘤与妊娠并存极为罕见，英文文献中报道的病例不到20例。我们报告一例马拉维妇女的病例，该妇女在肾切除、放疗和两线化疗后，孕期出现进展性高危转移性成人肾母细胞瘤。
