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孕期高危成人肾母细胞瘤:一例报告

High-Risk Adult Wilms' Tumour in Pregnancy: A Case Report.

作者信息

Kasenda Stephen, Mategula Donnie, Chiphangwi Noel, Gadama Luis Aaron, Masamba Leo Peter Lockie

机构信息

Blantyre District Health Office, Blantyre, Malawi.

Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi.

出版信息

Malawi Med J. 2019 Jun;31(2):155-158. doi: 10.4314/mmj.v31i2.9.

Abstract

Wilms' tumour is the most common renal neoplasm in children with an incidence of 10 cases per 1 million children and a median age at diagnosis of 3.5 years. In Western countries its occurrence in adults is 0.2 cases per million people in western countries and carries a poorer prognosis. The co-existence of Adult Wilms' tumour and pregnancy is extremely rare with less than 20 cases published in the English literature. We present a case of a Malawian woman who had progressive high-risk metastatic Adult Wilms' tumour in pregnancy after nephrectomy, radiotherapy and two lines of chemotherapy.

摘要

肾母细胞瘤是儿童最常见的肾脏肿瘤,发病率为每100万儿童中有10例,诊断时的中位年龄为3.5岁。在西方国家,其在成人中的发病率为每百万人0.2例,预后较差。成人肾母细胞瘤与妊娠并存极为罕见,英文文献中报道的病例不到20例。我们报告一例马拉维妇女的病例,该妇女在肾切除、放疗和两线化疗后,孕期出现进展性高危转移性成人肾母细胞瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c3d/6698624/983aea6f4e6c/MMJ3102-0155Fig2.jpg

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