Dabek Robert J, Roh Daniel S, Ozdemir Derman, Austen William G, Bojovic Branko
Plastic Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, USA.
Internal Medicine, Saba University School of Medicine, The Bottom, Caribbean Netherlands, NLD.
Cureus. 2019 Jun 19;11(6):e4943. doi: 10.7759/cureus.4943.
Alopecia areata (AA) affects approximately 2.1% of the population, with women being affected more often than men. Current therapies consisting of topical corticosteroids or intralesional injections are often the first choices for treatment, but are limited by unsatisfactory outcomes or risks to patients. Recently, fractional lasers and microneedling, with or without the addition of topical agents, have been examined as treatment options. A literature review was performed to evaluate the efficacy of fractional lasers in the treatment of AA. A total of six fractional lasers and two microneedling studies consisting of small prospective and retrospective studies, and case reports were reviewed. The number of trials and participants are limited, but evidence suggests that fractional lasers and microneedling may be effective therapeutic approaches when coupled with topical agents. Larger studies are required to better understand the effects of these treatment modalities for AA.
斑秃（AA）影响着约2.1%的人口，女性比男性更常受到影响。目前由外用皮质类固醇或皮损内注射组成的疗法通常是治疗的首选，但受到疗效不尽人意或对患者有风险的限制。最近，分数激光和微针疗法，无论是否添加外用药物，都已作为治疗选择进行了研究。进行了一项文献综述以评估分数激光治疗AA的疗效。总共回顾了六项分数激光和两项微针疗法的研究，这些研究包括小型前瞻性和回顾性研究以及病例报告。试验数量和参与者有限，但有证据表明，分数激光和微针疗法与外用药物联合使用时可能是有效的治疗方法。需要进行更大规模的研究，以更好地了解这些治疗方式对AA的影响。
