Samaddar Arghadip, Sharma Anuradha, Kumar Ph Akhilesh, Srivastava Saumya, Shrimali Twishi, Gopalakrishnan Maya, Bohra Gopal Krishna
Department of Microbiology, All India Institute of Medical Sciences, Jodhpur, 342005, Rajasthan, India.
Department of General Medicine, All India Institute of Medical Sciences, Jodhpur, 342005, Rajasthan, India.
Med Mycol Case Rep. 2019 Aug 1;25:49-52. doi: 10.1016/j.mmcr.2019.07.012. eCollection 2019 Sep.
Histoplasmosis is a systemic fungal disease caused by dimorphic fungus and is more common in immunocompromised patients. We report two cases of disseminated histoplasmosis in immunocompetent individuals from a non-endemic zone in Western India. Rapid diagnostic tests like urinary antigen detection and molecular assays comprise the need of the hour as early initiation of antifungal therapy can be life-saving. Clinicians need to be aware of this entity to prevent misdiagnosis and initiate prompt effective management.
组织胞浆菌病是一种由双相真菌引起的全身性真菌疾病,在免疫功能低下的患者中更为常见。我们报告了两例来自印度西部非流行区的免疫功能正常个体发生播散性组织胞浆菌病的病例。像尿抗原检测和分子检测这样的快速诊断测试是当务之急,因为尽早开始抗真菌治疗可能挽救生命。临床医生需要了解这种疾病,以防止误诊并及时开展有效的治疗。