组织胞浆菌尿抗原低阳性结果的临床意义
Clinical significance of low-positive histoplasma urine antigen results.
作者信息
Theel Elitza S, Ramanan Poornima
机构信息
Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA
Division of Infectious Diseases, Mayo Clinic Health System, Eau Claire, Wisconsin, USA.
出版信息
J Clin Microbiol. 2014 Sep;52(9):3444-6. doi: 10.1128/JCM.01598-14. Epub 2014 Jul 16.
Abstract
Histoplasma urine antigen (UAg) detection is an important biomarker for histoplasmosis. The clinical significance of low-positive (<0.6 ng/ml) UAg results was evaluated in 25 patients without evidence of prior Histoplasma infection. UAg results from 12/25 (48%) patients were considered falsely positive, suggesting that low-positive UAg values should be interpreted cautiously.
摘要
组织胞浆菌尿抗原（UAg）检测是组织胞浆菌病的一项重要生物标志物。对25例无既往组织胞浆菌感染证据的患者评估了低阳性（<0.6 ng/ml）UAg结果的临床意义。25例患者中有12例（48%）的UAg结果被认为是假阳性，这表明对低阳性UAg值的解读应谨慎。
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