黄斑裂孔手术联合内界膜剥除术后视网膜毛细血管的区域密度和视网膜敏感性
REGIONAL DENSITIES OF RETINAL CAPILLARIES AND RETINAL SENSITIVITIES AFTER MACULAR HOLE SURGERY WITH INTERNAL LIMITING MEMBRANE PEELING.
作者信息
Baba Takayuki, Kakisu Masato, Nizawa Tomohiro, Oshitari Toshiyuki, Yamamoto Shuichi
机构信息
Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, Japan.
出版信息
Retina. 2020 Aug;40(8):1585-1591. doi: 10.1097/IAE.0000000000002637.
PURPOSE
To measure the vascular density (VD) of the retinal capillary plexuses by optical coherence tomography angiography (OCTA) after surgery for an idiopathic macular hole.
METHODS
Retrospective, observational case series.Sixteen eyes of 16 patients with an idiopathic macular hole underwent vitrectomy with internal limiting membrane peeling. The VDs of the superficial capillary plexus (SCP) and deep capillary plexus (DCP) were determined by OCTA, and the retinal sensitivity (RS) and the inner retinal thickness (IRT) were measured before, and at 3, 6, and 12 months after the surgery. The VD, RS, and IRT were measured at the four parafoveal quadrants.
RESULTS
The mean age was 68.9 years. The VDs of the SCP and DCP were significantly correlated with the RS and IRT at 12 months postoperatively (all P < 0.001 for both SCP and DCP). The VDs of the SCP and DCP were higher, the RS more sensitive, and the IRT thicker in the nasal than the temporal quadrant at 12 months (P < 0.001, <0.001, =0.009, <0.001, respectively).
CONCLUSION
The significant correlation between the VDs of the SCP and DCP and the RS and IRT may be due to the nasal shift of the posterior retina.
目的
通过光学相干断层扫描血管造影（OCTA）测量特发性黄斑裂孔手术后视网膜毛细血管丛的血管密度（VD）。
方法
回顾性观察病例系列。16例特发性黄斑裂孔患者的16只眼接受了玻璃体切除术联合内界膜剥除术。通过OCTA测定浅表毛细血管丛（SCP）和深部毛细血管丛（DCP）的VD，并在手术前以及手术后3、6和12个月测量视网膜敏感度（RS）和视网膜内层厚度（IRT）。在四个黄斑旁象限测量VD、RS和IRT。
结果
平均年龄为68.9岁。术后12个月时，SCP和DCP的VD与RS和IRT显著相关（SCP和DCP的P值均<0.001）。术后12个月时，SCP和DCP的VD在鼻侧象限高于颞侧象限，RS更敏感，IRT更厚（P值分别为<0.001、<0.001、=0.009、<0.001）。
结论
SCP和DCP的VD与RS和IRT之间的显著相关性可能是由于视网膜后部向鼻侧移位所致。
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