Department of Radiotherapy, Lishui Central Hospital, Lishui, China.
Department of Emergency, Zhuji People's Hospital of Zhejiang Province, Zhuji, China.
Thorac Cancer. 2019 Oct;10(10):2050-2053. doi: 10.1111/1759-7714.13182. Epub 2019 Aug 27.
Multiple primary malignant tumors (MPMTs) are rarely seen among the patients with malignant neoplasms. Moreover, the existence of five MPMTs in the same patient is an extremely rare phenomenon. In this case, a 42-year-old male patient developed five metachronous MPMTs within 16 years and the duration between each malignant tumor shortened with the progression of the disease. Multidisciplinary treatments were used on this patient and he fought against the cancers until the end of his life. Our report provides us with a new awareness of MPMTs, which should be considered when we come across with cancer patients who develop various unexplainable symptoms after the diagnosis of the first neoplasm.
多原发恶性肿瘤（MPMT）在恶性肿瘤患者中罕见，而同一患者同时存在五种 MPMT 极为罕见。本文报道了 16 年内先后发生 5 种不同部位、5 次恶性肿瘤的 1 例 42 岁男性患者，且随着病情进展，两次恶性肿瘤发生的时间间隔逐渐缩短。该患者接受了多学科治疗，并与癌症抗争到生命的最后一刻。本病例提示我们，在遇到首次恶性肿瘤诊断后出现多种不明原因症状的癌症患者时，应考虑到 MPMT 的可能。
