Department of Cosmetic Raw Materials Chemistry, Medical University of Lodz, Lodz, Poland.
Department of Cosmetology and Aesthetic Dermatology, Medical University of Lodz, Lodz, Poland.
J Dermatolog Treat. 2021 May;32(3):291-296. doi: 10.1080/09546634.2019.1657222. Epub 2019 Aug 28.
Acne is a common, chronic, inflammatory disease of the pilosebaceous unit. It has a significant impact on patient quality of life, especially when lesions occur on cosmetically sensitive areas. Chemical peeling is a well-known option in the treatment of acne vulgaris, but little is known about azelaic acid (AZA) peels.
To determine the efficacy of 30% AZA peel, in decreasing the amount of secreted sebum, and reducing acne lesions.
The study involved 35 women, with acne lesions on face skin. All the subjects underwent a series of six treatments, performed every 2 weeks.
A series of treatments contributed to a statistically significant reduction in the amount of secreted sebum. Similarly, highly significant values determining the overall number of acne lesions and the severity of the disease according to the IGA scale were also changed. The procedure was well tolerated by all participants.
Peels with 30% AZA reduced acne lesions and normalized the activity of the sebaceous glands. The reduction of sebum allows us to believe that obtained good results in patients will be stable and long-lasting.
痤疮是一种常见的、慢性的、累及毛囊皮脂腺单位的炎症性疾病。它对患者的生活质量有重大影响，尤其是病变发生在美容敏感区域时。化学焕肤是治疗寻常痤疮的一种知名方法，但对于壬二酸（AZA）焕肤知之甚少。
确定 30%AZA 焕肤治疗减少皮脂分泌和减少痤疮皮损的疗效。
这项研究纳入了 35 名面部有痤疮皮损的女性患者。所有患者均接受了一系列共 6 次的治疗，每 2 周进行一次。
一系列治疗显著减少了皮脂分泌量。同样，根据 IGA 量表评估的痤疮总皮损数和疾病严重程度的重要指标也发生了显著变化。所有参与者均能耐受该程序。
30%AZA 焕肤可减少痤疮皮损并使皮脂腺活动正常化。皮脂减少使我们相信，在患者中获得的良好效果将是稳定且持久的。
