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早发性精神分裂症与就业、收入、教育和同居状况的关联:一项全国性研究,随访 35 年。

The association between early-onset schizophrenia with employment, income, education, and cohabitation status: nationwide study with 35 years of follow-up.

机构信息

Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, P.O. Box 21, 00014, Helsinki, Finland.

iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2019 Nov;54(11):1343-1351. doi: 10.1007/s00127-019-01756-0. Epub 2019 Aug 27.

DOI:10.1007/s00127-019-01756-0
PMID:31456027
Abstract

PURPOSE

Individuals with schizophrenia have been reported to have low employment rates. We examined the associations of schizophrenia with employment, income, and status of cohabitation from a work life course perspective.

METHODS

Nationwide cohort study including all individuals (n = 2,390,127) born in Denmark between 1955 and 1991, who were alive at their 25th birthday. Diagnosis of schizophrenia (yes/no) between ages 15 and 25 was used as an exposure. Employment status, annual wage or self-employment earnings, level of education, and cohabitant status from the age of 25-61 (years 1980-2016) were used as outcomes.

RESULTS

Schizophrenia diagnosis between ages 15 and 25 (n = 9448) was associated with higher odds of not being employed (at the age of 30: OR 39.4, 95% CI 36.5-42.6), having no secondary or higher education (7.4, 7.0-7.8), and living alone (7.6, 7.2-8.1). These odds ratios were two-to-three times lower and decreasing over time for those individuals who did not receive treatment in a psychiatric inpatient or outpatient clinic for schizophrenia after the age of 25. Between ages 25-61, individuals with schizophrenia have cumulative earning of $224,000, which is 14% of the amount that the individuals who have not been diagnosed with schizophrenia earn.

CONCLUSIONS

Individuals with schizophrenia are at high risk of being outside the labour market and living alone throughout their entire life, resulting in an enormous societal loss in earnings. Individuals with less chronic course of schizophrenia had a gradual but substantial improvement throughout their work life.

摘要

目的

据报道,精神分裂症患者的就业率较低。我们从工作生活历程的角度研究了精神分裂症与就业、收入和同居状况的关系。

方法

这项全国性队列研究纳入了所有(n=2390127)1955 年至 1991 年期间出生于丹麦且在 25 岁生日时仍在世的个体。15 至 25 岁之间诊断为精神分裂症(是/否)被用作暴露因素。25 至 61 岁(1980 年至 2016 年)的就业状况、年薪或自营职业收入、教育程度和同居状况被用作结局。

结果

15 至 25 岁之间诊断为精神分裂症(n=9448)的个体与就业可能性降低相关(30 岁时,比值比 39.4,95%置信区间 36.5-42.6),具有中学或更高学历的可能性降低(7.4,7.0-7.8),独居的可能性增加(7.6,7.2-8.1)。这些比值比在那些在 25 岁后没有在精神病门诊接受精神分裂症住院或门诊治疗的个体中要低 2 至 3 倍,且随着时间的推移而逐渐降低。在 25 至 61 岁期间,精神分裂症患者的累计收入为 224000 美元,这是未被诊断出患有精神分裂症的个体收入的 14%。

结论

精神分裂症患者面临着长期脱离劳动力市场和独居的高风险,这导致了巨大的社会收入损失。精神分裂症病程较轻的个体在整个工作生涯中逐渐但实质性地改善。

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