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促肾上腺皮质激素和卵巢静脉取样在产生孕激素的肾上腺肿瘤中的应用及文献复习。

The utility of adrenal and ovarian venous sampling in a progesterone-producing adrenal tumor and review of the literature.

机构信息

Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, 100730, Beijing, China.

Department of Respiratory, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, 100730, Beijing, China.

出版信息

Endocrine. 2019 Nov;66(2):319-325. doi: 10.1007/s12020-019-02007-7. Epub 2019 Aug 27.

Abstract

PURPOSE

A clinical case presenting secondary amenorrhea accompanied by an adrenal adenoma and hyperprogesteronemia is described in this study.

METHODS

Selective catheterization and sampling of adrenal and ovarian veins were performed.

RESULTS

The source of hyperprogesteronemia was located in the right adrenal gland. A progesterone-producing tumor in the right adrenal gland was diagnosed and removed. Twenty-six days after tumor resection, menstruation occurred.

CONCLUSIONS

Progesterone-producing tumors should be considered with the presence of an adrenal mass and hyperprogesteronemia. Combined adrenal and ovarian venous sampling may help to identify the source of progesterone secretion.

摘要

目的

本研究描述了一例伴有肾上腺腺瘤和孕激素血症的继发性闭经临床病例。

方法

进行选择性肾上腺和卵巢静脉插管和取样。

结果

孕激素血症的来源定位于右侧肾上腺。诊断出右侧肾上腺产生孕激素的肿瘤,并进行了切除。肿瘤切除后 26 天,月经恢复。

结论

当存在肾上腺肿块和孕激素血症时,应考虑孕激素产生肿瘤。联合肾上腺和卵巢静脉取样可能有助于确定孕激素分泌的来源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e691/6838047/68450087749f/12020_2019_2007_Fig1_HTML.jpg

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