Organic Chemistry Laboratory, Bayreuth, Germany.
Adv Exp Med Biol. 2019;1152:253-270. doi: 10.1007/978-3-030-20301-6_13.
Breast cancer represents the major cause of death in female cancer patients. New efficient treatments are desperately needed, particularly especially for patients suffering from advanced stages and metastases, or those who are no longer responding to the clinically established drugs such as cisplatin or carboplatin. New promising therapy regimens and platinum complexes have emerged over the last few years that displayed efficacy in advanced platinum- and/or drug-resistant breast tumors and metastases. This chapter provides an overview of the latest developments in the field of platinum-based drugs against advanced and resistant breast cancers since 2013.
乳腺癌是女性癌症患者死亡的主要原因。特别特别需要新的有效治疗方法，特别是对于患有晚期和转移的患者，或那些对顺铂或卡铂等临床确立的药物不再有反应的患者。在过去几年中，出现了新的有前途的治疗方案和铂配合物，它们在晚期铂和/或耐药性乳腺癌肿瘤和转移中显示出疗效。本章概述了自 2013 年以来针对晚期和耐药性乳腺癌的铂类药物领域的最新进展。
