Niğde Ömer Halisdemir Training and Research Hospital, Niğde, Turkey.
Department of Child and Adolescent Psychiatry, Faculty of Medicine, Marmara University, İstanbul, Turkey.
Pediatr Pulmonol. 2019 Dec;54(12):1927-1935. doi: 10.1002/ppul.24492. Epub 2019 Aug 27.
Many psychological factors contribute to an increased risk of depression in children and adolescents with cystic fibrosis (CF). This study aims to evaluate coexisting psychiatric disorders, perceived social support, and quality of life (QoL) in Turkish children with CF and compare these factors with those of a control group.
The study group consisted of 32 children (8-16 years of age) with CF and a group of 33 age- and sex-matched control children. All subjects completed the Children's Depression Inventory (CDI), Screen for Child Anxiety and Related Disorders (SCARED), Social Support Appraisals Scale, and Pediatric Quality of Life Questionnaire. Psychiatric diagnoses were established using the Kiddie Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version.
Of the children with CF, 80% of those in the 8 to 11 years age range and 50% of those in the 12 to 17 years age range had at least one psychiatric disorder, that is, 68% of the 33 children with CF had at least one psychiatric disorder. Anxiety disorder (46.8%) and attention deficit and hyperactivity disorder (21.8%) were also common among children with CF. The rates of depression in the CF group and control group were 21.9% and 6.1%, respectively (P > .05). The CF subjects with coexisting depression exhibited higher levels of disease severity, longer periods of hospitalization, and more frequent anxiety disorder. When compared with the control group, the QoL among the Turkish children with CF was lower (P < .05). The CDI and SCARED are relatively sensitive and specific screening tools for depression and anxiety in children with CF.
Psychiatric disorders were more frequently found in children and adolescents with CF. By examining symptoms of anxiety and depression and by using screening tools, CF patients who exhibit symptoms of psychiatric disorders can be better identified and evaluated.
许多心理因素会增加儿童和青少年囊性纤维化（CF）患者患抑郁症的风险。本研究旨在评估土耳其 CF 患儿共存的精神障碍、感知到的社会支持和生活质量（QoL），并将这些因素与对照组进行比较。
研究组由 32 名（8-16 岁）CF 患儿和 33 名年龄和性别匹配的对照组儿童组成。所有受试者均完成了儿童抑郁量表（CDI）、儿童焦虑相关障碍筛查量表（SCARED）、社会支持评估量表和儿童生活质量问卷。使用 Kiddie 情感障碍和精神分裂症谱系及终生版本进行精神病学诊断。
在 CF 患儿中，80%的 8-11 岁患儿和 50%的 12-17 岁患儿至少有一种精神障碍，即 33 名 CF 患儿中有 68%至少有一种精神障碍。焦虑障碍（46.8%）和注意缺陷多动障碍（21.8%）在 CF 患儿中也很常见。CF 组和对照组的抑郁发生率分别为 21.9%和 6.1%（P＞0.05）。合并抑郁的 CF 患儿疾病严重程度更高、住院时间更长、焦虑障碍更频繁。与对照组相比，土耳其 CF 患儿的生活质量较低（P＜0.05）。CDI 和 SCARED 是评估 CF 患儿抑郁和焦虑的相对敏感和特异的筛查工具。
CF 患儿中更常发现精神障碍。通过检查焦虑和抑郁症状并使用筛查工具，可以更好地识别和评估表现出精神障碍症状的 CF 患者。
