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原发性甲状腺弥漫性大B细胞淋巴瘤与甲状腺乳头状癌并存:一例报告及文献复习

Coexistence of primary thyroid diffuse large B cell lymphoma and papillary thyroid carcinoma: a case report and literature review.

作者信息

Chen Ling, Liu Yihui, Dong Chunhui

机构信息

Department of Oncology, First Affiliated Hospital of Xi'an Jiao Tong University, Xi'an, China.

Cancer Center, People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, China.

出版信息

J Int Med Res. 2019 Oct;47(10):5289-5293. doi: 10.1177/0300060519869133. Epub 2019 Aug 28.

Abstract

Primary thyroid lymphoma (PTL) is a very rare type of thyroid malignant tumor. PTL coexisting with papillary thyroid carcinoma (PTC) is even scarcer and can be easily overlooked. We present our experience of the diagnosis and treatment of a 37-year-old woman with primary thyroid diffuse large B cell lymphoma complicated with PTC. We also considered this case in the context of previous reports. The results indicated that the incidence of concurrent Hashimoto’s disease varied among patients with different lymphoma subtypes, with the highest incidence in patients with mucosa-associated lymphoid tissue lymphoma. Furthermore, thyroid cancer and thus the combination of PTL and PTC were more common in women.

摘要

原发性甲状腺淋巴瘤(PTL)是一种非常罕见的甲状腺恶性肿瘤。PTL与甲状腺乳头状癌(PTC)共存的情况更为罕见,很容易被忽视。我们介绍了一位37岁女性原发性甲状腺弥漫性大B细胞淋巴瘤合并PTC的诊断和治疗经验。我们还结合既往报道对该病例进行了分析。结果表明,不同淋巴瘤亚型患者中合并桥本氏病的发生率有所不同,黏膜相关淋巴组织淋巴瘤患者的发生率最高。此外,甲状腺癌以及PTL与PTC的合并情况在女性中更为常见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b666/6833368/dec2fa201400/10.1177_0300060519869133-fig1.jpg

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