Kong Ling, Shen Zheng, Zhang Wei, Xia Meng, Gu Minyan, Zhou Xuefei, Zhang Yalei
National Engineering Research Center of Protected Agriculture and State Key Laboratory of Pollution Control and Resource Reuse, Tongji University, Shanghai 200092, China.
ACS Omega. 2018 Dec 17;3(12):17430-17438. doi: 10.1021/acsomega.8b02179. eCollection 2018 Dec 31.
The utilization of sucrose, an easily accessible disaccharide, in the production of a versatile platform chemical lactic acid (LA), is more attractive than a monosaccharide. In this work, we report a modification approach by 3-aminopropyltrimethoxysilane to introduce an amino group onto the surface of the Sn-Beta Lewis acid catalyst. Using the modified catalyst, a maximum LA yield of 58% was achieved under optimal hydrothermal conditions (190 °C, 4 h) from sucrose, along with a complete conversion and a reduced 5-hydroxymethylfurfural (HMF) yield of 8% compared to Sn-Beta. To evaluate the role of the amino group, different substrates were used as the reactants to produce LA. The experimental results suggested that both fructose and glucose were crucial intermediates in the initial 2 h, whereas glucose is the sole reactant after 2 h. Upon modification, not only the hydrolysis of sucrose was promoted, but the side reaction of HMF formation was also suppressed.
利用易于获取的二糖蔗糖生产多功能平台化学品乳酸（LA）比利用单糖更具吸引力。在这项工作中，我们报道了一种通过3-氨丙基三甲氧基硅烷进行改性的方法，以在Sn-Beta路易斯酸催化剂表面引入氨基。使用改性催化剂，在最佳水热条件（190°C，4小时）下，以蔗糖为原料，乳酸的最大产率达到58%，同时实现了完全转化，与Sn-Beta相比，5-羟甲基糠醛（HMF）的产率降低至8%。为了评估氨基的作用，使用不同的底物作为反应物来生产乳酸。实验结果表明，果糖和葡萄糖在最初2小时内都是关键中间体，而2小时后葡萄糖是唯一的反应物。改性后，不仅促进了蔗糖的水解，还抑制了HMF形成的副反应。
