Talbi Imen, Efrit Mohamed Lotfi, Touil Soufiane
Laboratory of Heteroatom Organic Chemistry, Faculty of Sciences of Bizerte, University of Carthage, 7021 Zarzouna, Tunisia.
Laboratoire de Synthèse Organique Sélective et Hétérocyclique-Evaluation de l'Activité Biologique, Faculté des Sciences de Tunis, Université de Tunis El Manar, Tunis 2092, Tunisia.
ACS Omega. 2018 May 9;3(5):5078-5082. doi: 10.1021/acsomega.8b00544. eCollection 2018 May 31.
Three efficient and high-yielding procedures have been developed for the conversion of primary amides into nitriles, mediated by hitherto unexplored P(NMe), PCl, or P(OPh). The reactions were conducted under operationally simple and mild conditions and displayed broad substrate scope and good functional group tolerance.
已经开发出三种高效高产的方法，用于将伯酰胺转化为腈，该转化过程由此前未被探索过的P(NMe)、PCl或P(OPh)介导。反应在操作简单且温和的条件下进行，具有广泛的底物范围和良好的官能团耐受性。
