Lamey P J, Darwaza A, Fisher B M, Samaranayake L P, Macfarlane T W, Frier B M
Department of Oral Medicine and Pathology, Glasgow Dental Hospital and School, Scotland.
J Oral Pathol. 1988 Aug;17(7):354-7. doi: 10.1111/j.1600-0714.1988.tb01549.x.
One hundred and nine patients with diabetes mellitus and 100 age-, sex- and denture-status-matched, non-diabetic individuals were investigated prospectively. Comparison was made of oral candidal carriage, clinical infection and inherited ability to secrete blood group antigens in saliva. Diabetic patients had a significantly higher prevalence of oral candidal carriage and infection (P less than 0.001) than non-diabetic individuals, but the candidal load between the 2 groups, was not significant. A comparable proportion of insulin-dependent, non-insulin dependent and control groups were secretors of blood group antigens, and there was no difference in the oral candidal carriage and infection rates between secretors and non-secretors.
对109例糖尿病患者和100例年龄、性别及假牙佩戴情况相匹配的非糖尿病个体进行了前瞻性研究。比较了口腔念珠菌携带情况、临床感染情况以及唾液中分泌血型抗原的遗传能力。糖尿病患者口腔念珠菌携带和感染的患病率显著高于非糖尿病个体（P<0.001），但两组之间的念珠菌负荷无显著差异。胰岛素依赖型、非胰岛素依赖型和对照组中分泌血型抗原的比例相当，分泌者与非分泌者之间的口腔念珠菌携带率和感染率无差异。
