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水悬浮液中的微管蛋白极化率

Tubulin Polarizability in Aqueous Suspensions.

作者信息

Guzman-Sepulveda Jose Rafael, Wu Ruitao, Kalra Aarat P, Aminpour Maral, Tuszynski Jack A, Dogariu Aristide

机构信息

CREOL, The College of Optics and Photonics, University of Central Florida, Orlando 32816, United States.

Department of Physics and Department of Oncology, University of Alberta, Edmonton T6G 2R3, Canada.

出版信息

ACS Omega. 2019 May 23;4(5):9144-9149. doi: 10.1021/acsomega.9b00137. eCollection 2019 May 31.

DOI:10.1021/acsomega.9b00137
PMID:31460002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6648103/
Abstract

We report accurate optical measurements of tubulin polarizability in aqueous suspensions. We determined the dependence of polarizability on tubulin concentration and on the suspension's pH, providing benchmark numbers for quantifying the optical response of this protein in various artificial and cellular environments. We compare our measurement data with a few estimates found in the previous literature and also with our simplified model estimations.

摘要

我们报告了在水性悬浮液中对微管蛋白极化率的精确光学测量。我们确定了极化率对微管蛋白浓度和悬浮液pH值的依赖性,为量化该蛋白质在各种人工和细胞环境中的光学响应提供了基准数据。我们将测量数据与先前文献中的一些估计值以及我们的简化模型估计值进行了比较。

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