Kurbanov V A, Nikolaeva L F, Dedov I I
Ter Arkh. 1988;60(9):57-61.
The paper is devoted to systemic analysis of changes of the hypophyseal hormones, sex and adrenal glands, and thyroid in men in the course of a year after MI. A stable state of the hypophyseal-gonadal system the first 2 mos after MI was followed by a significant decrease in prolactin, testosterone levels and an increase in estradiol concentration. A marked decrease in STH, cortisol, TSH and thyroid hormone levels, and monotonously decreased ("leveled") circadian rhythm of secretion of practically all hormones were revealed. Functional exercise tests have shown switching over of the neuroendocrine system of MI patients to a special sparing regimen functioning at a qualitatively new hormonal-metabolic level rather than its depletion.
本文致力于对心肌梗死(MI)后男性患者在一年时间内垂体激素、性腺、肾上腺及甲状腺变化的系统分析。MI后最初两个月垂体-性腺系统处于稳定状态,随后催乳素、睾酮水平显著下降,雌二醇浓度升高。生长激素(STH)、皮质醇、促甲状腺激素(TSH)及甲状腺激素水平明显降低,几乎所有激素的昼夜分泌节律呈单调下降(“平稳”)状态。功能运动试验表明,MI患者的神经内分泌系统转向一种特殊的节约机制,在全新的激素-代谢水平上发挥作用,而非功能耗竭。