Shiihara Jun, Ohta Hiromitsu, Ikeda Satoshi, Baba Tomohisa, Okudera Koji, Ogura Takashi
Department of Respiratory Medicine Kanagawa Cardiovascular and Respiratory Center Kanagawa Japan.
Department of Respiratory Medicine Jichi Medical University Saitama Medical Center Saitama Japan.
Respirol Case Rep. 2019 Aug 23;7(8):e00475. doi: 10.1002/rcr2.475. eCollection 2019 Nov.
Erdheim-Chester disease (ECD), a rare form of non-Langerhans cell histiocytosis, affects long bones, the retroperitoneal region, and the central nervous, cardiovascular, and pulmonary systems. Most patients with ECD show interlobular septal thickening, centrilobular micronodules, and ground glass opacities on chest computed tomography (CT). We encountered a 66-year-old man with ECD who presented at first visit with randomly distributed multiple pulmonary nodules and who then developed large tumour shadows, observed on chest CT. To our knowledge, this random distribution pattern of multiple pulmonary nodules has not previously been reported.
厄德里希-切斯特病（ECD）是一种罕见的非朗格汉斯细胞组织细胞增多症，可累及长骨、腹膜后区域以及中枢神经、心血管和肺部系统。大多数ECD患者在胸部计算机断层扫描（CT）上表现为小叶间隔增厚、小叶中心微结节和磨玻璃影。我们遇到一名66岁的ECD男性患者，初诊时胸部CT显示有随机分布的多个肺结节，随后出现了较大的肿瘤阴影。据我们所知，这种多个肺结节的随机分布模式此前尚未见报道。
