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不伴有长骨受累的 Erdheim-Chester 病表现

Erdheim-Chester Disease Manifesting Without Long Bone Involvement.

作者信息

Sivasubramanian Dhiran, Balasubramanian Karthick, Mohamed Kalifa Mohamed Raghib Hussain, Sanil Sathwik, Aravind Smrti, Palanisamy Nithish Nanda, Senthilkumar Virushnee

机构信息

Department of Cardiology Children's Hospital of Philadelphia Philadelphia Pennsylvania USA.

Department of Critical Care Medicine Christian Medical College Vellore India.

出版信息

Respirol Case Rep. 2025 Jun 10;13(6):e70237. doi: 10.1002/rcr2.70237. eCollection 2025 Jun.

DOI:10.1002/rcr2.70237
PMID:40503290
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12151790/
Abstract

Erdheim-Chester Disease (ECD) is an extremely rare, non-Langerhans cell histiocytosis characterised by the proliferation of foamy histiocytes infiltrating various organs. It almost always presents with osteosclerosis of the long bones, making our case atypical due to the absence of skeletal involvement despite widespread infiltration of other organs.

摘要

厄尔德海姆-切斯特病（ECD）是一种极其罕见的非朗格汉斯细胞组织细胞增多症，其特征为泡沫状组织细胞增殖并浸润各种器官。该病几乎总是伴有长骨骨硬化，而我们的病例因尽管其他器官广泛浸润但无骨骼受累而显得不典型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a660/12151790/95ea4b67ea02/RCR2-13-e70237-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a660/12151790/05750430e914/RCR2-13-e70237-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a660/12151790/985e42585871/RCR2-13-e70237-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a660/12151790/95ea4b67ea02/RCR2-13-e70237-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a660/12151790/05750430e914/RCR2-13-e70237-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a660/12151790/985e42585871/RCR2-13-e70237-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a660/12151790/95ea4b67ea02/RCR2-13-e70237-g004.jpg

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本文引用的文献

1
Erdheim-Chester disease progression from miliary pulmonary nodules to large tumours.Erdheim-Chester病从粟粒性肺结节发展为大肿瘤。
Respirol Case Rep. 2019 Aug 23;7(8):e00475. doi: 10.1002/rcr2.475. eCollection 2019 Nov.
2
Bone involvement in Erdheim-Chester disease: imaging findings including periostitis and partial epiphyseal involvement.骨受累于厄尔德海姆-切斯特病：影像学表现包括骨膜炎和部分骨骺受累。
Radiology. 2006 Feb;238(2):632-9. doi: 10.1148/radiol.2382041525. Epub 2005 Dec 21.