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提供预防肺炎的疫苗——规划与财务问题

Delivering vaccines for the prevention of pneumonia - programmatic and financial issues.

作者信息

Otczyk Diana C, Cripps Allan W

机构信息

School of Medicine, Griffith Health Institute, Griffith University, Gold Coast Campus, Queensland, 4222 Australia.

出版信息

Pneumonia (Nathan). 2013 Feb 14;2:16-25. doi: 10.15172/pneu.2013.2/244. eCollection 2013.

Abstract

Pneumonia is the leading cause of morbidity and mortality in children younger than 5 years. Vaccines are available against the main bacterial pathogens type b and . There are also vaccines against measles and pertussis; diseases that can predispose a child to pneumonia. Partners such as the Global Alliance for Vaccines and Immunisation (GAVI), the Hib Initiative, the Accelerated Development and Introduction Plan for pneumococcal vaccines and the Measles Initiative, have accelerated the introduction of vaccines into developing countries. Whilst significant improvements in vaccine coverage have occurred globally over the past decade, there still remains an urgent need to scale-up key pneumonia protection and treatment interventions as identified in the Global Action Plan for the Prevention and Control of Pneumonia (GAPP). There is promise that global immunisation will continue to improve child survival. However, there are several challenges to vaccine implementation that must first be addressed, including: a lack of access to under-served and marginalised populations; inadequate planning and management; a lack of political commitment; weak monitoring and surveillance programmes and assured sustainable finance and supply of quality vaccines. There is an urgent need to increase global awareness of the devastation that pneumonia brings to the worlds poorest communities.

摘要

肺炎是5岁以下儿童发病和死亡的主要原因。有针对主要细菌病原体b型和(此处原文缺失内容)的疫苗。也有针对麻疹和百日咳的疫苗;这些疾病会使儿童易患肺炎。全球疫苗免疫联盟(GAVI)、b型流感嗜血杆菌(Hib)倡议、肺炎球菌疫苗加速开发和引进计划以及麻疹倡议等合作伙伴,加速了疫苗在发展中国家的引进。虽然在过去十年全球疫苗接种覆盖率有了显著提高,但仍迫切需要扩大《全球预防和控制肺炎行动计划》(GAPP)中确定的关键肺炎预防和治疗干预措施。全球免疫有望继续提高儿童存活率。然而,疫苗实施存在若干挑战,必须首先加以解决,包括:难以覆盖服务不足和边缘化人群;规划和管理不足;缺乏政治承诺;监测和监督计划薄弱以及确保优质疫苗的可持续资金和供应。迫切需要提高全球对肺炎给世界最贫困社区带来的破坏的认识。

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Serotype replacement after pneumococcal vaccination.肺炎球菌疫苗接种后的血清型替换
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