Department of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, 1300 S. Coulter Street, Amarillo, TX, 79106, USA.
Center for Blood Brain Barrier Research, TTUHSC, Amarillo, TX, 79106, USA.
Curr Cardiol Rep. 2019 Aug 28;21(10):111. doi: 10.1007/s11886-019-1204-y.
Tobacco continues to kill about 0.48 million Americans per year and there are currently 34.3 million smokers in the USA. As a consequence of the First Surgeon General's Report on Tobacco in 1964, tobacco control interventions on part of the government led to a significant decline in conventional tobacco product usage over the last few decades. However, more recently, a new entity in the form of electronic cigarettes has risen rapidly and has exposed a younger population to a plethora of dangerous consequences. Looking at e-cigarettes from the perspective of tobacco control however raises a lot of challenges. There is little doubt that existing smokers of combustible cigarettes who switch to e-cigarettes will be switching to a less harmful product. However, if the younger generation begins using e-cigarettes as a result of targeted marketing, appealing flavors and 'safer alternative' perception, decades of progress made in conventional tobacco control will be negated. Governments at the federal, state, and local levels have a mandate to once again implement new public health policies to ensure that non-conventional tobacco products like e-cigarettes are available as smoking cessation tools for existing smokers but at the same time do not play a role in ruining the health of future generations through addiction and disease. PURPOSE OF REVIEW: To review the present scenario of regulations and policies impacting public health with respect to electronic nicotine delivery systems (ENDS) with the objective of providing a meaningful and balanced view of the challenges at hand with plausible recommendations. RECENT FINDINGS: Nicotine in tobacco is known to cause addiction and dependence. It is particularly potent in children and young adults. E-cigarettes can deliver high concentrations of nicotine, and these concentrations can vary depending on the numerous constituents within the e-cigarette which vary greatly from one another. Use of e-cigarettes is implicated as a risk factor for future cigarette use in young adults. Moreover, e-cigarette usage patterns also depend on several sociodemographic factors. Banning tobacco products has shown to reduce smoking risk in youth and as such, strong e-cigarette regulation measures are needed for prevention. Effective regulation of ENDS faces a multitude of challenges. One such challenge is to prevent youth and non-smokers from getting habituated to nicotine through e-cigarettes. The intention of tobacco companies to sustain sales through harmful marketing strategies that tone down the risks and highlight e-cigarettes as a "much safer alternative" while promoting flavors appealing to children should be immediately prohibited. Another hazard is the endorsement of ENDS as devices meant for enhancing social interaction which opens a path for youth to make erroneous choices under peer pressure. On the other hand, several studies have reported that e-cigarettes significantly reduce an existing smoker's risk of being exposed to toxic tobacco smoke constituents that are normally present in cigarette smoke. This leads to the conclusions that e-cigarettes can be a tool for smoking cessation for current smokers. Public policy must take a multi-dimensional approach to balance these two extremes.
烟草每年导致约 48 万美国人死亡,目前美国有 3430 万烟民。由于 1964 年第一任卫生总监关于烟草的报告,政府采取的烟草控制干预措施导致过去几十年传统烟草产品的使用显著下降。然而,最近一种以电子烟形式出现的新实体迅速崛起,使更多年轻人面临诸多危险后果。然而,从烟草控制的角度来看待电子烟,却带来了许多挑战。毫无疑问,那些从可燃香烟转而使用电子烟的现有吸烟者将转而使用危害性较小的产品。然而,如果年轻一代因为有针对性的营销、诱人的口味和“更安全的替代品”的认知而开始使用电子烟,那么在传统烟草控制方面取得的几十年进展将被否定。联邦、州和地方各级政府都有责任再次实施新的公共卫生政策,以确保电子烟等非传统烟草产品作为现有吸烟者的戒烟工具,但同时不会因成瘾和疾病而损害后代的健康。
目的综述:审查目前影响电子尼古丁输送系统(ENDS)公共卫生的法规和政策,目的是对当前面临的挑战提供有意义和平衡的看法,并提出合理的建议。
最新发现:众所周知,烟草中的尼古丁会导致成瘾和依赖。它在儿童和青少年中尤为强烈。电子烟可以输送高浓度的尼古丁,而且这些浓度会因电子烟中的许多成分而异,而这些成分彼此之间差异很大。使用电子烟被认为是年轻人未来使用香烟的一个风险因素。此外,电子烟的使用模式也取决于几个社会人口因素。禁止烟草制品已被证明可以降低年轻人的吸烟风险,因此需要采取强有力的电子烟监管措施来预防。有效监管 ENDS 面临着许多挑战。其中一个挑战是防止青少年和非吸烟者通过电子烟对尼古丁上瘾。烟草公司通过有害的营销策略来维持销售的意图,这些策略淡化了风险,并将电子烟宣传为“更安全的替代品”,同时推广吸引儿童的口味,应立即禁止这些策略。另一个危险是将 ENDS 作为旨在增强社交互动的设备加以认可,这为年轻人在同伴压力下做出错误选择开辟了道路。另一方面,几项研究报告称,电子烟显著降低了现有吸烟者接触香烟烟雾中通常存在的有毒烟草烟雾成分的风险。这就得出结论,电子烟可以成为现有吸烟者戒烟的工具。公共政策必须采取多维度的方法来平衡这两个极端。