MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou 350108, P. R. China.
Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20892, USA.
Chem Soc Rev. 2019 Oct 7;48(19):5140-5176. doi: 10.1039/c9cs00011a. Epub 2019 Aug 29.
This review contributes towards a systematic understanding of the mechanism of shape-dependent effects on nanoparticles (NPs) for elaborating and predicting their properties and applications based on the past two decades of research. Recently, the significance of shape-dependent physical chemistry and biomedicine has drawn ever increasing attention. While there has been a great deal of effort to utilize NPs with different morphologies in these fields, so far research studies are largely localized in particular materials, synthetic methods, or biomedical applications, and have ignored the interactional and interdependent relationships of these areas. This review is a comprehensive description of the NP shapes from theory, synthesis, property to application. We figure out the roles that shape plays in the properties of different kinds of nanomaterials together with physicochemical and biomedical applications. Through systematic elaboration of these shape-dependent impacts, better utilization of nanomaterials with diverse morphologies would be realized and definite strategies would be expected for breakthroughs in these fields. In addition, we have proposed some critical challenges and open problems that need to be addressed in nanotechnology.
这篇综述有助于系统地理解纳米粒子（NPs）的形状依赖性效应的机制，以便在过去二十年的研究基础上，详细阐述和预测它们的性质和应用。最近，形状依赖性物理化学和生物医学的重要性引起了越来越多的关注。虽然在这些领域已经投入了大量的精力来利用具有不同形态的 NPs，但到目前为止，研究工作主要集中在特定的材料、合成方法或生物医学应用上，而忽略了这些领域的相互作用和相互依存关系。这篇综述全面描述了从理论、合成、性质到应用的 NP 形状。我们研究了形状在不同种类纳米材料的性质中的作用，以及它们在物理化学和生物医学应用中的作用。通过系统地阐述这些形状依赖性的影响，可以更好地利用具有不同形态的纳米材料，并有望在这些领域取得突破。此外，我们还提出了纳米技术中需要解决的一些关键挑战和开放性问题。
